Signaling mechanisms that mediate invasion in prostate cancer cells
Recent evidence indicates that androgen‐sensitive prostate cancer cells have a less
malignant phenotype characterized by reduced migration and invasion. We investigated …
malignant phenotype characterized by reduced migration and invasion. We investigated …
The androgen receptor and prostate cancer invasion
Recent evidence indicates that androgen-sensitive prostate cancer cells are characterized
by a less pronounced malignant phenotype. We demonstrate that transfection with an …
by a less pronounced malignant phenotype. We demonstrate that transfection with an …
The androgen receptor associates with the epidermal growth factor receptor in androgen-sensitive prostate cancer cells
Many recent evidences indicate that androgen-sensitive prostate cancer cells have a lower
malignant phenotype that is in particular characterized by a reduced migration and invasion …
malignant phenotype that is in particular characterized by a reduced migration and invasion …
EGF receptor (EGFR) signaling promoting invasion is disrupted in androgen‐sensitive prostate cancer cells by an interaction between EGFR and androgen receptor …
L Bonaccorsi, V Carloni, M Muratori… - … Journal of Cancer, 2004 - Wiley Online Library
We previously demonstrated that expression of androgen receptor (AR) by transfection of
the androgen‐independent prostate cancer cell line PC3 decreases invasion and adhesion …
the androgen‐independent prostate cancer cell line PC3 decreases invasion and adhesion …
Androgen receptor and prostate cancer invasion1
L Bonaccorsi, M Muratori, V Carloni… - … journal of andrology, 2003 - Wiley Online Library
Evidence indicates that androgen‐sensitive prostate cancer cells have a lower malignant
potential. We previously demonstrated that expression of androgen receptor (AR) by …
potential. We previously demonstrated that expression of androgen receptor (AR) by …
Gefitinib ('IRESSA', ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3 K/AKT activation
Purpose Androgen-independent prostate cancer (AI-PC) is characterized by a higher
invasive potential compared to hormone-responsive prostate cancer. A therapeutic option …
invasive potential compared to hormone-responsive prostate cancer. A therapeutic option …
Altered endocytosis of epidermal growth factor receptor in androgen receptor positive prostate cancer cell lines
L Bonaccorsi, D Nosi, M Muratori… - Journal of …, 2007 - jme.bioscientifica.com
Although androgens and the androgen receptor (AR) are involved in tumorigenesis of
prostate cancer (PC) in initial phases, less clear is the role played in advanced androgen …
prostate cancer (PC) in initial phases, less clear is the role played in advanced androgen …
Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice
The activation of epidermal growth factor receptor (EGF-R) plays a key role in the promotion
of proliferation and invasion in prostatic carcinoma (PCa). Gefitinib (Iressa; ZD1839), an …
of proliferation and invasion in prostatic carcinoma (PCa). Gefitinib (Iressa; ZD1839), an …
EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells
T Turnert, P Chen, LJ Goodly, A NWells - Clinical & experimental …, 1996 - Springer
Carcinomas of the prostate and other lineages often present an autocrine stimulatory loop
acting via the EGF receptor (EGFR). We have recently shown that EGFR-mediated signals …
acting via the EGF receptor (EGFR). We have recently shown that EGFR-mediated signals …
Mitogenic signaling in androgen sensitive and insensitive prostate cancer cell lines
C Guo, LM Luttrell, DT Price - The Journal of urology, 2000 - Elsevier
PURPOSE:: To investigate the role of a specific mitogen activated protein kinase,
extracellular signal-regulated kinase (ERK), in regulating cell proliferation induced by three …
extracellular signal-regulated kinase (ERK), in regulating cell proliferation induced by three …