Higher plasma urate level is reported to be associated with a reduced risk and slower
progression of Parkinson's disease (PD). In this study, we explored the effects of urate on …

There is evidence to support that oxidative stress is increased in Parkinson's disease (PD)
and contributes to the degeneration of dopaminergic neurons. Recent research has shown …

Uric acid has neuroprotective effect on Parkinson's disease (PD) by inhibiting oxidative
damage and neuronal cell death. Our previous study has shown that uric acid protected …

Background Multiple risk factors contribute to the progression of Parkinson's disease,
including oxidative stress and neuroinflammation. Epidemiological studies have revealed a …

Urate is a major antioxidant as well as the enzymatic end product of purine metabolism in
humans. Higher levels correlate with a reduced risk of developing Parkinson's disease (PD) …

Urate has emerged as a promising target for neuroprotection based on epidemiological
observations, preclinical models, and early clinical trial results in multiple neurologic …

Background: Parkinson's Disease (PD) is characterized by both motor and non-motor
symptoms. The presynaptic neuronal protein, α-Synuclein, plays a pivotal role in PD …

Urate is the end product of purine metabolism and a major antioxidant circulating in humans.
Recent data link higher levels of urate with a reduced risk of developing Parkinson's disease …

Parkinson's disease (PD) is an age associated, progressive and a second most common
neurodegenerative disease. It is caused due to degeneration of dopaminergic neurons in …

Parkinson's disease (PD) is a progressive neurodegenerative disorder and characterized by
motor system disorders resulting in loss of dopaminergic (DA) neurons. CXC195, a novel …