[PDF][PDF] H‐chain ferritin: a natural nuclei targeting and bioactive delivery nanovector

L Zhang, L Li, A Di Penta, U Carmona… - Advanced healthcare …, 2015 - researchgate.net
DOI: 10.1002/adhm. 201500226 natural cellular uptake and furthermore allowing nuclear
targeting. Besides the cargo, apoferritin itself is biologically active due to its intrinsic iron …

Ferritin nanocages: a novel platform for biomedical applications

B Bhushan, SU Kumar, I Matai… - Journal of …, 2014 - ingentaconnect.com
Ferritin is a ubiquitous iron storage protein responsible for maintaining the iron homeostasis
in living organism and thereby protects the cell from oxidative damage. The ferritin protein …

Ferritin: a multifunctional nanoplatform for biological detection, imaging diagnosis, and drug delivery

N Song, J Zhang, J Zhai, J Hong, C Yuan… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Ferritins are spherical iron storage proteins within cells that are composed of a
combination of 24 subunits of two types, heavy-chain ferritin (HFn) and light-chain ferritin …

[HTML][HTML] Functional ferritin nanoparticles for biomedical applications

Z Wang, H Gao, Y Zhang, G Liu, G Niu… - Frontiers of chemical …, 2017 - Springer
Ferritin, a major iron storage protein with a hollow interior cavity, has been reported recently
to play many important roles in biomedical and bioengineering applications. Owing to the …

Cargo loading within ferritin nanocages in preparation for tumor-targeted delivery

J Zhang, D Cheng, J He, J Hong, C Yuan, M Liang - Nature Protocols, 2021 - nature.com
Ferritins are spherical iron storage proteins within cells, composed of 24 subunits of two
types, heavy-chain ferritin (HFn) and light-chain ferritin. Ferritins auto-assemble naturally …

Humanized archaeal ferritin as a tool for cell targeted delivery

V De Turris, MC Trabuco, G Peruzzi, A Boffi, C Testi… - Nanoscale, 2017 - pubs.rsc.org
Human ferritins have been extensively studied to be used as nanocarriers for diverse
applications and could represent a convenient alternative for targeted delivery of anticancer …

[HTML][HTML] Ferritin–a multifaceted protein scaffold for biotherapeutics

NK Lee, S Cho, IS Kim - Experimental & Molecular Medicine, 2022 - nature.com
The ferritin nanocage is an endogenous protein that exists in almost all mammals. Its hollow
spherical structure that naturally stores iron ions has been diversely exploited by …

[HTML][HTML] Bioengineered ferritin nanocarriers for cancer therapy

X Sun, Y Hong, Y Gong, S Zheng, D Xie - International Journal of …, 2021 - mdpi.com
Ferritin naturally exists in most organisms and can specifically recognize the transferrin 1
receptor (TfR1), which is generally highly expressed on various types of tumor cells. The pH …

[HTML][HTML] Ferritin-based nanomedicine for disease treatment

Y Zhu, Y Zhu, T Cao, X Liu, X Liu, Y Yan, Y Shi… - Medical …, 2023 - degruyter.com
Ferritin is an endogenous protein which is self-assembled by 24 subunits into a highly
uniform nanocage structure. Due to the drug-encapsulating ability in the hollow inner cavity …

Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics

NK Lee, EJ Lee, S Kim, G Nam, M Kih, Y Hong… - Journal of Controlled …, 2017 - Elsevier
Ferritin nanocages are of particular interest as a novel platform for drug and vaccine
delivery, diagnosis, biomineralization scaffold and more, due to their perfect and complex …