Novel bio-therapeutic agents that harness the properties of small, non-coding nucleic acids
hold great promise for clinical applications. These include antisense oligonucleotides that …

RNA therapeutics is a rapidly emerging field of biotherapeutics based upon a powerful and
versatile platform with a nearly unlimited capacity to address unmet clinical needs. These …

Since our knowledge on structure and function of messenger RNA (mRNA) has expanded
from merely being an intermediate molecule between DNA and proteins to the notion that …

Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …

RNA therapeutics hold significant promise in the treatment of cardiovascular diseases.
RNAs are biologically diverse and functionally specific and can be used for gain-or loss-of …

Purpose of Review RNA therapeutics are a new and rapidly expanding class of drugs to
prevent or treat a wide spectrum of diseases. We discuss the defining characteristics of the …

Noncoding RNA provides a versatile mechanism of gene regulation and thereby present as
novel targets for intervention in various cardiovascular disease. Future studies aimed at …

Long noncoding RNAs in cardiovascular disease, diagnosis, an... : Current Opinion in
Cardiology Long noncoding RNAs in cardiovascular disease, diagnosis, and therapy : Current …

Cardiovascular disease (CVD) remains the biggest killer globally, driven in part by the
ageing population andlack of recent advances in diagnostic and prognostic tools and …

It is now appreciated that over 90% of the human genome is comprised of noncoding RNAs
that have the ability to affect other components of the genome and regulate gene …