Cardiomyocytes from embryonic stem cells: towards human therapy

G Földes, SE Harding, NN Ali - Expert Opinion on Biological …, 2008 - Taylor & Francis
Background: Despite improvements in survival with current therapies, it is now clear that
major cardiovascular event rates in patients remain high. Cardiac cell replacement therapy …

[HTML][HTML] Sources of cardiomyocytes for stem cell therapy: an update

P Gallo, C Peschle, G Condorelli - Pediatric research, 2006 - nature.com
The therapeutic use of stem cells for cardiac repair following myocardial infarction (MI) has
generated a great deal of interest. Many types of stem/progenitor cells have been used in an …

Myocardial regeneration strategies using human embryonic stem cell-derived cardiomyocytes

O Capi, L Gepstein - Journal of controlled release, 2006 - Elsevier
Regenerative medicine is a new biomedicine discipline that takes advantage of the recent
advancements in the fields of stem cell biology, molecular biology, and tissue engineering to …

A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair

M Wysoczynski, R Bolli - European heart journal, 2020 - academic.oup.com
Despite the well-documented capacity of embryonic stem cells (ESCs) to differentiate into
cardiomyocytes, transplantation of ESCs or ESC-derived cells is plagued by several …

Embryonic stem cells pace the heart

P Menasche - Nature biotechnology, 2004 - nature.com
Embryonic stem cells pace the heart | Nature Biotechnology Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

[HTML][HTML] Advances and research in congenital heart disease

A Dodge-Khatami - Translational Pediatrics, 2016 - ncbi.nlm.nih.gov
© Translational Pediatrics. All rights reserved. Transl Pediatr 2016; 5 (3): 109-111 tp.
amegroups. com patients yet unborn. What are some of the future directions which research …

[HTML][HTML] New aspects in the diagnosis and therapy of fetal hypoplastic left heart syndrome

O Graupner, C Enzensberger… - Geburtshilfe und …, 2019 - thieme-connect.com
Fetal hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease with a
lethal prognosis without postnatal therapeutic intervention or surgery. The aim of this article …

Endogenous cardiac stem cells for the treatment of heart failure

T Fuentes, M Kearns-Jonker - Stem cells and cloning: advances …, 2013 - Taylor & Francis
Stem cell-based therapies hold promise for regenerating the myocardium after injury.
Recent data obtained from phase I clinical trials using endogenous cardiovascular …

Large animal models for cardiac stem cell therapies

F Gandolfi, A Vanelli, G Pennarossa, M Rahaman… - Theriogenology, 2011 - Elsevier
Cardiovascular disease is the leading cause of death in developed countries and is one of
the leading causes of disease burden in developing countries. Therapies have markedly …

Growth and differentiation of human embryonic stem cells for cardiac cell replacement therapy

C Xu, J Lebkowski, JD Gold - Current Stem Cell Research & …, 2006 - ingentaconnect.com
Due to the limited proliferation capacity of cardiac cells, cell replacement therapy has been
proposed to restore cardiac function in patients suffering from ischemic heart disease and …