OBJECTIVES: Cardiopulmonary bypass surgery is complicated by metabolic acidosis,
microvascular dysfunction, and capillary leak. The glycocalyx—a layer of proteins and …

Background There is no doubt today about the existence of the endothelial glycocalyx (EG)
and its decisive role in maintaining vascular homeostasis in adult humans. Shedding of the …

OBJECTIVES: To assess the disruption of endothelial glycocalyx integrity in children with
sepsis receiving fluid resuscitation with either balanced or unbalanced crystalloids. The …

Objective The association between the shedding of the endothelial glycocalyx (EG) and the
pathogenesis of microcirculatory perfusion disturbances has been discussed in …

Cardiopulmonary bypass (CPB) remains a necessary component for the surgical repair of
many congenital heart defects. As such, there is an ever-present risk of known complications …

Background Sepsis-associated destruction of the pulmonary microvascular endothelial
glycocalyx (EGCX) creates a vulnerable endothelial surface, contributing to the development …

The vascular endothelium is the interface between circulating blood and end organs and
thus has a critical role in preserving organ function. The endothelium is lined by a glycan …

Objective Perturbation of the endothelial glycocalyx is discussed in the pathogenesis of
complications related to cardiopulmonary bypass. We evaluated the effects of …

Background Corticosteroids are used in paediatric heart surgery to attenuate systemic
inflammatory response. Glycocalyx regulates vascular permeability, shear stress and cell …

Objective The objective of this study was to evaluate the association between serum
albumin levels and microcirculation changes, glycocalyx degradation, and the clinical …