[HTML][HTML] Trends of nanotechnology in type 2 diabetes mellitus treatment

YV Simos, K Spyrou, M Patila, N Karouta… - Asian journal of …, 2021 - Elsevier
There are several therapeutic approaches in type 2 diabetes mellitus (T2DM). When diet
and exercise fail to control hyperglycemia, patients are forced to start therapy with …

Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles

X Li, S Guo, C Zhu, Q Zhu, Y Gan, J Rantanen… - Biomaterials, 2013 - Elsevier
Chitosan nanoparticles (NC) have excellent capacity for protein entrapment, favorable
epithelial permeability, and are regarded as promising nanocarriers for oral protein delivery …

Nanomedicine for treatment of diabetes in an aging population: state-of-the-art and future developments

S Krol, R Ellis-Behnke, P Marchetti - Maturitas, 2012 - Elsevier
Nowadays diabetes, especially type 2 diabetes (which is strongly related to the Western diet
and life-style), has developed worldwide into an epidemic disease. Nanomedicine aims to …

Insulin-and cholic acid-loaded zein/casein–dextran nanoparticles enhance the oral absorption and hypoglycemic effect of insulin

X Bao, K Qian, P Yao - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Diabetes mellitus is the most common metabolic disease in the world. Herein, insulin-and
cholic acid-loaded zein nanoparticles with dextran surfaces were fabricated to enhance the …

[HTML][HTML] Preparation and characterization of a novel smart polymeric hydrogel for drug delivery of insulin

B Jafari, F Rafie, S Davaran - BioImpacts: BI, 2011 - ncbi.nlm.nih.gov
Methods NIPAAm-MAA-HEM copolymers were synthesized by radical chain reaction with
86: 4: 10 (5% w/v) ratios respectively. Reaction was carried out in 1, 4-Dioxane under …

[引用][C] Oral delivery of insulin for treatment of diabetes: classical challenges and current opportunities

MJ Ansari - Journal of Medical Sciences, 2015 - Asian Network for Scientific …

Thiolated nanoparticles overcome the mucus barrier and epithelial barrier for oral delivery of insulin

S Zhou, H Deng, Y Zhang, P Wu, B He… - Molecular …, 2019 - ACS Publications
Oral administration is an ideal alternative for drug delivery due to its convenience and safety.
However, oral protein delivery is limited by biological barriers such as the mucus barrier and …

[HTML][HTML] Polymer-based nanoparticle strategies for insulin delivery

S Mansoor, PPD Kondiah, YE Choonara, V Pillay - Polymers, 2019 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic illness estimated to have affected 451 million
individuals to date, with this number expected to significantly rise in the coming years. There …

Transdermal delivery of insulin via microneedles

RJ Narayan - Journal of Biomedical Nanotechnology, 2014 - ingentaconnect.com
Treatment of insulin-dependent diabetes mellitus, also known as Type 1 diabetes mellitus,
requires delivery of exogenous insulin via injection or pump. An alternative to syringe-based …

[HTML][HTML] Nanotechnological approaches in diabetes treatment: A new horizon

A Samadder, AR Khuda-Bukhsh - World Journal of Translational …, 2014 - wjgnet.com
Diabetes is a chronic metabolic disorder that affects millions of people worldwide and takes
a heavy toll on human life. Treatment of diabetics often poses a problem in selection of the …