Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP) and SP plus
azithromycin (SPAZ) reduces low birthweight (< 2,500 g) in women without malarial and …

Background Intermittent preventive treatment in pregnancy has not been evaluated outside
of Africa. Low birthweight (LBW,< 2,500 g) is common in Papua New Guinea (PNG) and …

Background Poor pregnancy and birth outcomes are common in sub-Saharan Africa and
have complex aetiologies. Sulfadoxine-pyrimethamine (SP), given for intermittent preventive …

Background Malaria in pregnancy is associated with adverse birth outcomes. However, the
underlying mechanisms remain poorly understood. Tight regulation of angiogenic …

Objective To examine the potential to reduce foetal and neonatal growth faltering through
intermittent preventive treatment in pregnancy (IPT p) of malaria and reproductive tract …

Background Malaria and hypertension are major causes of maternal mortality in tropical
countries, especially during first pregnancies, but evidence for a relationship between these …

Background Malaria in early pregnancy is a risk factor for preterm birth and is associated
with sustained inflammation and dysregulated angiogenesis across gestation. This study …

Background Exposure during pregnancy to malaria and sexually-transmitted infections is
associated with adverse birth outcomes including low birth weight (LBW). This study aimed …

Preterm delivery, which is associated with infections during pregnancy, is common in sub-
Saharan Africa. We enrolled 1,320 pregnant women into a randomized, controlled trial in …

Malaria infection during pregnancy is associated with adverse birth outcomes but underlying
mechanisms are poorly understood. Here, we discuss the impact of malaria in pregnancy on …