Long-term care facility (LTCF) older residents display physiological alterations of cellular
and humoral immunity that affect vaccine responses. Preliminary reports suggested a low …

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing COVID-19 hospitalization and fatal outcome. However, several …

Clinical and biological assessment of the COVID-19 vaccine efficacy in the frail population is
of crucial importance. The study focuses on measuring the levels of anti-SARS-CoV-2 IgG …

Whether age-associated defects in T cells impact the immunogenicity and reactogenicity of
mRNA vaccines remains unclear. Using a vaccinated cohort (n= 216), we demonstrated that …

Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease 2019 (COVID-19), is modifying human activity all over the world with significant …

The emergence of new SARS-CoV-2 variants, such as the more transmissible Delta and
Omicron variants, has raised concerns on efficacy of the COVID-19 vaccines. Here, we …

To date there has been limited head-to-head evaluation of immune responses to different
types of COVID-19 vaccines. A real-world population-based longitudinal study was …

An effective vaccine is needed to end the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic. Here, we assess the preliminary safety, tolerability and …

Background Understanding and measuring the individual level of immune protection and its
persistence at both humoral and cellular levels after SARS-CoV-2 vaccination is mandatory …