Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

T Fotsis, M Pepper, H Adlercreutz… - Proceedings of the …, 1993 - National Acad Sciences
Consumption of a plant-based diet can prevent the development and progression of chronic
diseases that are associated with extensive neovascularization; however, little is known …

Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis

T Fotsis, M Pepper, H Adlercreutz, T Hase… - The Journal of …, 1995 - Elsevier
Consumption of a plant-based diet can prevent the development and progression of chronic
diseases that are associated with extensive neovascularization. To determine whether …

Flavonoids, Dietary-derived Inhibitors of Cell Proliferation and in Vitro Angiogenesis

T Fotsis, MS Pepper, E Aktas, S Breit, S Rasku… - Cancer research, 1997 - AACR
Consumption of a plant-based diet can prevent the development and progression of chronic
diseases associated with extensive neovascularization, including solid malignant tumors. In …

[HTML][HTML] Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice

RC Santell, N Kieu, WG Helferich - The Journal of nutrition, 2000 - Elsevier
The studies presented were conducted to assess the effect of the soy isoflavone genistein
on proliferation of estrogen-independent human breast cancer cells (MDA-MB-231) in vitro …

Evaluation of the biochemical targets of genistein in tumor cells

G Peterson - The Journal of nutrition, 1995 - Elsevier
Although data from epidemiological studies and cancer models suggest that genistein plays
an important role in cancer prevention, the biochemical target (s) of genistein action is (are) …

Antiangiogenic mechanisms of diet-derived polyphenols

Y Cao, R Cao, E Bråkenhielm - The Journal of Nutritional Biochemistry, 2002 - Elsevier
Accumulating evidence demonstrates that polyphenols in natural products are beneficial
against human lethal diseases such as cancer and metastasis. The underlying mechanisms …

Effect of genistein on in vitro and in vivo models of cancer

S Barnes - The Journal of nutrition, 1995 - Elsevier
In two–thirds of studies of the effect of genistein-containing soy materials in animal models of
cancer, the risk of cancer (incidence, latency or tumor number) was significantly reduced. In …

7Phytoestrogens and inhibition of angiogenesis

T Fotsis, MS Pepper, R Montesano, E Aktas… - Bailliere's clinical …, 1998 - Elsevier
The consumption of a plant-based diet can prevent the development and progression
ofchronic diseases associated with extensive neovascularization, including the progression …

Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer

HG Farina, M Pomies, DF Alonso… - Oncology …, 2006 - spandidos-publications.com
Tumor invasion, angiogenesis and metastasis involve secretion of proteolytic enzymes and
cell migration into blood vessels. Tumor cells are capable of degrading the extracellular …

Thrombotic mechanisms in atherosclerosis: potential impact of soy proteins

JN Wilcox, BF Blumenthal - The Journal of nutrition, 1995 - Elsevier
Generally injuries that remove or disrupt the endothelial cells lining blood vessels stimulate
formation of vascular lesions composed of smooth muscle cells. One of the first events after …