Stem cell-mediated gene delivering for the treatment of cerebral ischemia: progress and prospectives
Ischemic stroke is one of the leading causes of death and disability worldwide. There is no
effective treatment for ischemic stroke apart from thrombolytic therapy, which has a narrow …
effective treatment for ischemic stroke apart from thrombolytic therapy, which has a narrow …
Mesenchymal stem cell therapy in stroke: a systematic review of literature in pre-clinical and clinical research
H Zheng, B Zhang, PY Chhatbar, Y Dong… - Cell …, 2018 - journals.sagepub.com
Exogenous stem cell therapy (SCT) has been recognized recently as a promising
neuroregenerative strategy to augment recovery in stroke survivors. Mesenchymal stem …
neuroregenerative strategy to augment recovery in stroke survivors. Mesenchymal stem …
[HTML][HTML] Mesenchymal stem cell therapy in ischemic stroke trials. A systematic review
EM Gallego, MZ Castillo - Regenerative Therapy, 2024 - Elsevier
Cerebrovascular accidents, also known as strokes, are the leading cause of permanent
disability in society, presenting significant socioeconomic and healthcare costs. They can be …
disability in society, presenting significant socioeconomic and healthcare costs. They can be …
Mesenchymal stromal cells rescue cortical neurons from apoptotic cell death in an in vitro model of cerebral ischemia
Cell therapy with mesenchymal stromal cells (MSCs) was found to protect neurons from
damage after experimental stroke and is currently under investigation in clinical stroke trials …
damage after experimental stroke and is currently under investigation in clinical stroke trials …
[HTML][HTML] Attenuation of postischemic genomic alteration by mesenchymal stem cells: a microarray study
C Choi, SH Oh, JE Noh, YW Jeong, S Kim, JJ Ko… - Molecules and cells, 2016 - Elsevier
Intravenous administration of mesenchymal stem cells (IV-MSC) protects the ischemic rat
brain in a stroke model, but the molecular mechanism underlying its therapeutic effect is …
brain in a stroke model, but the molecular mechanism underlying its therapeutic effect is …
[PDF][PDF] Stand alone or join forces? Stem cell therapy for stroke
DI Abraham, M Gonzales, A Ibarra… - Expert Opin. Biol …, 2019 - researchgate.net
Introduction: Stroke is a major cause of mortality and disability with a narrow therapeutic
window. Stem cell therapy may enhance the stroke recovery. Areas Covered: Regenerative …
window. Stem cell therapy may enhance the stroke recovery. Areas Covered: Regenerative …
Human mesenchymal stromal cells and their derivative, SB623 cells, rescue neural cells via trophic support following in vitro ischemia
CC Tate, C Fonck, M McGrogan… - Cell …, 2010 - journals.sagepub.com
Cell transplantation is a promising treatment strategy for many neurological disorders,
including stroke, which can target multiple therapeutic mechanisms in a sustained fashion …
including stroke, which can target multiple therapeutic mechanisms in a sustained fashion …
[HTML][HTML] MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases
H Zhou, Y He, W Xiong, S Jing, X Duan, Z Huang… - Bioactive materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …
owing to their plasticity and accessibility. They possess several inherent characteristics …
[HTML][HTML] Mesenchymal stem cell-based therapy for ischemic stroke
JD Anderson, MT Pham, Z Contreras, M Hoon… - Chinese Neurosurgical …, 2016 - Springer
Ischemic stroke represents a major, worldwide health burden with increasing incidence.
Patients affected by ischemic strokes currently have few clinically approved treatment …
Patients affected by ischemic strokes currently have few clinically approved treatment …
Progress in mesenchymal stem cell therapy for ischemic stroke
Y Guo, Y Peng, H Zeng, G Chen - Stem cells international, 2021 - Wiley Online Library
Ischemic stroke (IS) is a serious cerebrovascular disease with high morbidity and disability
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …