Changes in the gap junctional intercellular communication in renal tubular epithelial cells in vitro treated with renal carcinogens
M Noguchi, K Nomata, J Watanabe, H Kanetake… - Cancer letters, 1998 - Elsevier
Gap junctional intercellular communications (GJIC) are known as the channels for the direct
transfer of cytoplasmic molecules between neighboring cells and are lost during …
transfer of cytoplasmic molecules between neighboring cells and are lost during …
Disruption of gap junctional intercellular communication in human renal cancer cell lines
M Noguchi, K Nomata, J Watanabe, H Sato… - Urology, 1999 - Elsevier
Objectives. Gap junctional intercellular communication (GJIC) is believed to play an
important role in the maintenance of cell homeostasis, and its disruption may be associated …
important role in the maintenance of cell homeostasis, and its disruption may be associated …
Modulation of gap junctional intercellular communication by EGF in human kidney epithelial cells
E Rivedal, S Mollerup, A Haugen, G Vikhamar - Carcinogenesis, 1996 - academic.oup.com
Modulation of gap junctional intercellular communication (GJIC) was studied in a multistep
model of human renal epithelial carcinogenesis. We report that the majority of primary …
model of human renal epithelial carcinogenesis. We report that the majority of primary …
Increased gap junctional intercellular communication capacity and connexin 43 and 26 expression in rat bladder carcinogenesis
M Asamoto, S Takahashi, K Imaida, T Shirai… - …, 1994 - academic.oup.com
Many reports have suggested that gap junctional intercellular communication or gap
junction proteins (connexins) could have tumor suppression characteristics. We investigated …
junction proteins (connexins) could have tumor suppression characteristics. We investigated …
Differential effects of renal carcinogens and tumor promoters on growth promotion and inhibition of gap junctional communication in two rat renal epithelial cell lines
N Konishi, PJ Donovan, JM Ward - Carcinogenesis, 1990 - academic.oup.com
To evaluate the effects of renal carcinogens and tumor promoters on gap junctional
intercellular communication (IC) and colony formation, two rat kidney epithelial cell lines …
intercellular communication (IC) and colony formation, two rat kidney epithelial cell lines …
Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis
A rat liver gap junction (GJ) cDNA probe that detects mRNA encoding the 32 Kd GJ‐protein
(connexin 32) was employed to study GJ‐protein gene expression in rat liver tumors …
(connexin 32) was employed to study GJ‐protein gene expression in rat liver tumors …
Enhanced tumorigenicity of rat bladder squamous cell carcinoma cells after abrogation of gap junctional intercellular communication
M Asamoto, H Toriyama‐Baba… - Japanese journal of …, 1998 - Wiley Online Library
We previously demonstrated a clear tendency for actively communicating rat bladder
carcinoma cell lines with elevated expression of connexin 43 mRNA to possess strong …
carcinoma cell lines with elevated expression of connexin 43 mRNA to possess strong …
Gap-junctional communication alterations at various regulatory levels of connexin expression and function during animal and human carcinogenesis
The loss of homeostasis which characterizes tumor growth is probably the result of a
deregulated intercellular communication capacity of the cancer cells. The deregulation of …
deregulated intercellular communication capacity of the cancer cells. The deregulation of …
Inhibition of intrinsic gap‐junction intercellular communication and enhancement of tumorigenicity of the rat bladder carcinoma cell line BC31 by a dominant‐negative …
VA Krutovskikh, H Yamasaki, H Tsuda… - … in cooperation with …, 1998 - Wiley Online Library
The tumor‐suppressive property of the connexin gap‐junction proteins was postulated from
the fact that their function of cell coupling is impaired in most cancer cells. However, in …
the fact that their function of cell coupling is impaired in most cancer cells. However, in …
Neoplastic phenotype of gap‐junctional intercellular communication–deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32
RS Rae, PP Mehta, CC Chang… - … in cooperation with …, 1998 - Wiley Online Library
Gap‐junctional intercellular communication (GJIC) is involved in cellular growth control and
is often reduced in neoplastic cells. In this study, four GJIC‐deficient rat liver epithelial cell …
is often reduced in neoplastic cells. In this study, four GJIC‐deficient rat liver epithelial cell …
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