We explore the impact of various polymers and their molecular weight on the stabilization of
wet-milled suspensions of itraconazole (ITZ), a poorly soluble drug, and its dissolution from …

Dissolution of poorly soluble drugs can be improved by wet-milling their suspensions and
drying the suspensions to form nanocomposites. Different classes of dispersants and their …

Nanoparticles, of the poorly water-soluble drug, itraconazole (ITZ), were produced by the
Advanced Evaporative Precipitation into Aqueous Solution process (Advanced EPAS). This …

Itraconazole (ITZ), a broad spectrum antifungal, is used orally for the treatment of wide range
of systemic fungal diseases; it's extremely poor water solubility mainly causes erratic …

This study is aimed at seeking an alternative dispersant for spray drying of drug
nanosuspensions. The ideal dispersant is not only able to prevent the agglomeration of drug …

Itraconazole (ITZ) nanocrystal-containing powders were prepared through the combined use
of high pressure homogenization (HPH) and spray drying (SD). These powders were …

There is more research required to broaden the knowledge on the downstream processing
of nanosuspensions into solid oral dosage forms, especially for coated nanosuspensions …

The objective of this study was to investigate the influence of stabilizer type on the
physicochemical properties, including dissolution, of ultra-high potency powders containing …

Formation of core-shell nanocomposites of Fenofibrate and Itraconazole, model poorly water
soluble drugs, via fluidized bed (FB) coating of their well-stabilized high drug loaded …

Bioavailability of a poorly soluble drug can be improved by preparing a drug
nanosuspension and subsequently drying it into nanocomposite microparticles (NCMPs) …