Traditional medicines have made impressive progress in treating various diseases. A Large
number of herbal plants are known to possess highly therapeutic properties which are useful …

The p38 mitogen‐activated protein kinase is activated by environmental stress and
cytokines and plays a role in transcriptional regulation and inflammatory responses. Factors …

In this study we describe a new comparative molecular field analysis (CoMFA) model of
dihydroquinazolinone and tetrasubstituted imidazole compounds with p38 MAPK inhibitory …

MAPKAPK2, a substrate of p38 MAPKs, plays central role in p38-mediated signal
transduction, and its inhibitors are promisingly useful in the treatment of inflammatory …

Inflammation, a widespread biological process linked to various diseases, poses a
significant global health challenge. Recent research targeting the development of new anti …

Benzimidazole derivatives occupied an important part in medicinal chemistry because of
their multifarious therapeutic actions. Inflammation is a protective response involving …

The process of inflammation is associated with several disorders such as cardiovascular
disease, cancer and arthritis. Cyclooxygenase (COX) receptors play an important role in …

The goal of this study is to look into the preliminary phytochemical and GC-MS analyses of a
methanol extract of the leaves of Acalypha indica. Alkaloids, tannins, steroids, saponins …

Purpose: To use in silico docking analysis and ADMET prediction of silibinin and glycyrrhetic
acid to determine their pharmacokinetic and pharmacodynamic properties as therapeutic …

Background: P38α, emerging as a hot spot for drug discovery, is a member of the mitogen-
activated protein kinase (MAPK) family and plays a crucial role in regulating the production …