Amyloid beta peptide (Aβ) can cause neurotoxicity in Alzheimer's disease (AD). It evokes a
cascade of oxidative damage to neurons. Pinocembrin (PCB), the most abundant flavonoid …

Background It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis
of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation …

Pinocembrin (PB), the most abundant flavonoid in propolis, has been proven to have
neuroprotective property against neurotoxicity in vivo and in vitro. Our recent study …

Pinocembrin (PB), the most abundant flavonoid in propolis, has been known to display
antioxidant activity. However, the mechanism as how PB can induce antioxidant activity …

Beta-Amyloid peptide (Aβ), a major protein component of brain senile plaques in
Alzheimer's disease (AD), has been considered as a critical cause in the pathogenesis of …

Excessive accumulation of β-amyloid (Aβ) is thought to be a major causative factor in the
pathogenesis of Alzheimer's disease (AD). Pretreating Aβ-induced neurotoxicity is a …

The pathogenic mechanism of neurodegenerative brain disorder such as Alzheimer's
disease (AD) has been still far from clearly understood. Previous research has identified that …

Amyloid β-protein (Aβ), which is deposited in neurons as neurofibrillary tangles, is known to
exert cytotoxic effects by inducing mitochondrial dysfunction. Additionally, the PI3K/Akt …

Beta-amyloid (Abeta)-induced neurotoxicity is considered to be mediated through the
formation of reactive oxygen species (ROS). In this study, the protective effects of Poria …

Alzheimer's disease (AD) is a major neurodegenerative brain disorder affecting about 14
million people worldwide. Aβ-induced cell injury is a crucial cause of neuronal loss in AD …