Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

Introduction: As with prescribing or continuing medications, deprescribing brings with it the
potential for harm as well as benefit. Uncertainty and avoidance of harm has been reported …

Background Managing polypharmacy is a challenge for healthcare systems globally. It is
also a health inequality concern as it can expose some of the most vulnerable in society to …

Background Knowledge of consumer (patient and caregiver) attitudes is essential for
conducting medication optimization in practice. Objectives The aim of this study was to …

Objectives Polypharmacy is a concern in the practice of geriatrics because of consequences
such as adverse drug events and poorer quality of life. Deprescribing, a response to …

Objective: Polypharmacy and adverse drug reactions are frequent and important among
older people. Few clinical trials have evaluated systematic withdrawal of medications among …

Background Deprescribing medication may be in response to an adverse clinical trigger
(reactive) or if future gains are unlikely to outweigh future harms (proactive). A hospital …

Inappropriate prescribing and polypharmacy in older persons are associated with increased
risks of falls, adverse drug events, hospital admissions, and death. 1-3 Given these potential …

In hospital deprescribing is the process of safely reducing or stopping medication use when
it is no longer necessary or potentially harmful. In the real world, successful implementation …

Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …