[HTML][HTML] Bawei chenxiang wan ameliorates cardiac hypertrophy by activating AMPK/PPAR-α signaling pathway improving energy metabolism

X Zhang, Z Zhang, P Wang, Y Han, L Liu, J Li… - Frontiers in …, 2021 - frontiersin.org
Bawei Chenxiang Wan (BCW), a well-known traditional Chinese Tibetan medicine formula,
is effective for the treatment of acute and chronic cardiovascular diseases. In the present …

[HTML][HTML] Bawei Chenxiang Wan ameliorates right ventricular hypertrophy in rats with high altitude heart disease by SIRT3-HIF1α-PDK/PDH signaling pathway …

Y Han, S Li, Z Zhang, X Ning, J Wu, X Zhang - … Medicine and Therapies, 2024 - Springer
Abstract Background Bawei Chenxiang Wan (BCW) is among the most effective and widely
used therapies for coronary heart disease and angina pectoris in Tibet. However, whether it …

1H NMR-based dynamic metabolomics delineates the therapeutic effects of Baoyuan decoction on isoproterenol-induced cardiac hypertrophy

Z Du, R Wen, Q Liu, J Wang, Y Lu, M Zhao… - … of pharmaceutical and …, 2019 - Elsevier
Cardiac hypertrophy (CH) is a major risk factor for many serious heart diseases. Sustained
CH is catastrophic, resulting in cardiac dysfunction that eventually leads to heart failure (HF) …

HypERlnc attenuates angiotensin II‐induced cardiomyocyte hypertrophy via promoting SIRT1 SUMOylation‐mediated activation of PGC‐1α/PPARα pathway in AC16 …

L Yue, S Sheng, M Yuan, J Lu, T Li… - Cell Biology …, 2023 - Wiley Online Library
Cardiac hypertrophy is a well‐established risk factor for cardiovascular mortality worldwide.
According to a recent study, hypoxia‐induced endoplasmic reticulum stress regulating long …

[HTML][HTML] Small-molecule 7, 8-dihydroxyflavone counteracts compensated and decompensated cardiac hypertrophy via AMPK activation

H Peng-Zhou, LI Pei-Feng, LIU Jie… - Journal of geriatric …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Pathological cardiac hypertrophy is a compensated response to various
stimuli and is considered a key risk factor for heart failure. 7, 8-Dihydroxyflavone (7, 8-DHF) …

Attenuation of cardiac remodeling by indole-3-carbinol in mice is associated with improved energy metabolism

W Deng, L Wei, J Zong, Z Bian… - International …, 2014 - internationaljournalofcardiology.com
Heart failure is one of the leading causes of mortality not only in the Western world but also
in China. The key pathophysiological process that ultimately leads to heart failure is cardiac …

Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway

X Li, P Zhang, Y Yang, J Wang, Y Zheng… - Acta Pharmacologica …, 2022 - nature.com
Cardiac hypertrophy is a common adaptive response to a variety of stimuli, but prolonged
hypertrophy leads to heart failure. Hence, discovery of agents treating cardiac hypertrophy is …

Atorvastatin attenuates cardiac hypertrophy through AMPK/miR-143-3p/Bcl2 axis

J Sun, C Zhang, Z Zhang - Archives of physiology and biochemistry, 2021 - Taylor & Francis
Atorvastatin is employed as a lipid lowering agent and its heart protective effect has been
recently reported as well. However, the mechanism of atorvastatin in attenuating cardiac …

Bicyclol attenuates obesity-induced cardiomyopathy via inhibiting NF-κB and MAPK signaling pathways

Y Chen, W Lin, L Zhong, Z Fang, B Ye, Z Wang… - … Drugs and Therapy, 2023 - Springer
Purpose Schisandra is a well-known traditional Chinese medicine in East Asia. As a
traditional Chinese medicine derivative with Schisandra chinensis as raw material, bicyclol …

Carnosol suppresses cardiomyocyte hypertrophy via promoting the activation of AMPK pathway

Y Tian, R Liu, Q Yang, J Zhang, Z Liu, B Dong… - Biochemical and …, 2024 - Elsevier
Pathological cardiac hypertrophy is associated with adverse cardiovascular events and can
gradually lead to heart failure, arrhythmia, and even sudden death. However, the current …