Pannexin: to gap or not to gap, is that a question?
G Dahl, S Locovei - IUBMB life, 2006 - Wiley Online Library
Vertebrates express two families of gap junction proteins: the well characterized connexins
and the recently discovered pannexins. The latter are related to invertebrate innexins. Here …
and the recently discovered pannexins. The latter are related to invertebrate innexins. Here …
Identification and characterization of pannexin expression in the mammalian cochlea
XH Wang, M Streeter, YP Liu… - Journal of Comparative …, 2009 - Wiley Online Library
The gap junction in vertebrates is encoded by the connexin gene family. Recently, a new
gene family termed pannexin (Panx) has been identified in vertebrates and found to encode …
gene family termed pannexin (Panx) has been identified in vertebrates and found to encode …
Pannexin‐1 in the CNS: Emerging concepts in health and disease
AK Yeung, CS Patil, MF Jackson - Journal of neurochemistry, 2020 - Wiley Online Library
Abstract Pannexin‐1 (Panx1) is a large pore membrane channel with unique conduction
properties ranging from non‐selective ion permeability to the extracellular release of …
properties ranging from non‐selective ion permeability to the extracellular release of …
Pannexins, distant relatives of the connexin family with specific cellular functions?
C D'hondt, R Ponsaerts, H De Smedt, G Bultynck… - …, 2009 - Wiley Online Library
Intercellular communication (IC) is mediated by gap junctions (GJs) and hemichannels,
which consist of proteins. This has been particularly well documented for the connexin (Cx) …
which consist of proteins. This has been particularly well documented for the connexin (Cx) …
Non-junction functions of pannexin-1 channels
BA MacVicar, RJ Thompson - Trends in neurosciences, 2010 - cell.com
Pannexins are large-pore ion channels with broad expression in the central nervous system
(CNS). The channels function by releasing large signaling molecules, such ATP and …
(CNS). The channels function by releasing large signaling molecules, such ATP and …
Connexins and pannexins: At the junction of neuro‐glial homeostasis & disease
AS Lapato, SK Tiwari‐Woodruff - Journal of neuroscience …, 2018 - Wiley Online Library
In the central nervous system (CNS), connexin (Cx) s and pannexin (Panx) s are an integral
component of homeostatic neuronal excitability and synaptic plasticity. Neuronal Cx gap …
component of homeostatic neuronal excitability and synaptic plasticity. Neuronal Cx gap …
ATP signaling is deficient in cultured Pannexin1‐null mouse astrocytes
Abstract Pannexins (Panx1, 2, and 3) comprise a group of proteins expressed in vertebrates
that share weak yet significant sequence homology with the invertebrate gap junction …
that share weak yet significant sequence homology with the invertebrate gap junction …
Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes
R Bruzzone, MT Barbe, NJ Jakob… - Journal of …, 2005 - Wiley Online Library
Several new findings have emphasized the role of neuron‐specific gap junction proteins
(connexins) and electrical synapses in processing sensory information and in synchronizing …
(connexins) and electrical synapses in processing sensory information and in synchronizing …
Identification of a potential regulator of the gap junction protein pannexin1
S Bunse, A Haghika, G Zoidl… - Cell communication & …, 2005 - Taylor & Francis
Recent studies have revealed a second class of gap-junction-forming proteins in
vertebrates. These genes are termed pannexins, and it has been suggested that they …
vertebrates. These genes are termed pannexins, and it has been suggested that they …