Emerging alternatives against Clostridioides difficile infection

A Romero-Rodríguez, CM de la Peña… - Anaerobe, 2022 - Elsevier
Clostridioides difficile infection (CDI) is a significant worry within healthcare institutions and
the community. It is one of the leading agents causing severe diarrhea worldwide. Effective …

[HTML][HTML] Frontiers in antibiotic alternatives for Clostridioides difficile infection

M Phanchana, P Harnvoravongchai… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) is a gram-positive, anaerobic spore-forming bacterium and
a major cause of antibiotic-associated diarrhea. Humans are naturally resistant to C. difficile …

Fighting against Clostridioides difficile infection: Current medications

M Quan, X Zhang, Q Fang, X Lv, X Wang… - International Journal of …, 2024 - Elsevier
Clostridioides difficile (formerly Clostridium difficile) has been regarded as an" urgent threat"
and a significant global health problem, as life-threatening diarrhea and refractory …

[HTML][HTML] Conventional and alternative treatment approaches for Clostridium difficile infection

KM Aljarallah - International journal of health sciences, 2017 - ncbi.nlm.nih.gov
Clostridium difficile-associated disease continues to be one of the leading health concerns
worldwide. C. difficile is considered as a causative agent of nosocomial diarrhea that causes …

Current and Ongoing Developments in Targeting Clostridioides difficile Infection and Recurrence

WY Cun, PA Keller, SG Pyne - Microorganisms, 2024 - mdpi.com
Clostridioides difficile is a Gram-positive, spore-forming anaerobic bacterial pathogen that
causes severe gastrointestinal infection in humans. This review provides background …

Antibiotic Treatment Pipeline for Clostridioides difficile Infection (CDI): A Wide Array of Narrow-Spectrum Agents

TJ Carlson, AJ Gonzales-Luna - Current Infectious Disease Reports, 2020 - Springer
Abstract Purpose of Review Clostridioides difficile infection (CDI) represents a major burden
on the US healthcare system. Despite the US Food and Drug Administration (FDA) approval …

Treatment issues in recurrent Clostridioides difficile infections and the possible role of germinants

N Budi, N Safdar, WE Rose - FEMS microbes, 2020 - academic.oup.com
Clostridioides difficile is the number one cause of hospital-acquired infections in the United
States and one of the CDC's urgent-level pathogen threats. The inflammation caused by …

Advances in Clostridioides difficile therapeutics

S Khanna - Expert Review of Anti-infective Therapy, 2021 - Taylor & Francis
Clostridioides difficile is an urgent public health threat by virtue of being the most common
pathogen in hospitals and an increased risk of community-acquired infection [1]. The …

Clostridioides (Clostridium) difficile infection: current and alternative therapeutic strategies

F Gil, IL Calderón, JA Fuentes… - Future …, 2018 - Future Medicine
Clostridioides difficile (C. difficile) has become a pathogen of worldwide importance
considering that epidemic strains are disseminated in hospitals of several countries, where …

Current Status of Nonantibiotic and Adjunct Therapies for Clostridium difficile Infection

N Suwantarat, DA Bobak - Current infectious disease reports, 2011 - Springer
Clostridium difficile infection (CDI) is a leading cause of nosocomial infections and the most
important cause of health care-associated diarrhea worldwide. Standard treatment of CDI …