Alternative Therapies for Clostridium difficile Infections

C Venuto, M Butler, ED Ashley… - … : The Journal of Human …, 2010 - Wiley Online Library
Clostridium difficile infection is a serious condition responsible for significant morbidity and
mortality, especially in patients being treated with antimicrobials. Increasing frequency of the …

Recurrent Clostridium difficile infection: from colonization to cure

K Shields, RV Araujo-Castillo, TG Theethira… - Anaerobe, 2015 - Elsevier
Clostridium difficile infection (CDI) is increasingly prevalent, dangerous and challenging to
prevent and manage. Despite intense national and international attention the incidence of …

Clostridioides difficile, a New “Superbug”

R Markovska, G Dimitrov, R Gergova, L Boyanova - Microorganisms, 2023 - mdpi.com
Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical
features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and …

The development of live biotherapeutics against Clostridioides difficile infection towards reconstituting gut microbiota

Y Zhang, A Saint Fleur, H Feng - Gut Microbes, 2022 - Taylor & Francis
Clostridioides difficile is the most prevalent pathogen of nosocomial diarrhea. In the United
States, over 450,000 cases of C. difficile infection (CDI), responsible for more than 29,000 …

Advances in the diagnosis and treatment of Clostridium difficile infections

Z Peng, L Ling, CW Stratton, C Li… - Emerging microbes & …, 2018 - Taylor & Francis
Clostridium difficile is a leading cause of antibiotic-associated diarrhea worldwide. The
diagnosis of C. difficile infection (CDI) requires both clinical manifestations and a positive …

[HTML][HTML] Management of Clostridium difficile infection

LS Al-Jashaami, HL DuPont - Gastroenterology & hepatology, 2016 - ncbi.nlm.nih.gov
Since the discovery of Clostridium difficile infection (CDI) in the 1970s, there has been an
increase in the incidence, severity, and recurrence rate of the disease. We reviewed the …

Clinical review of Clostridium difficile infection: an update on treatment and prevention

LM Daniels, WD Kufel - Expert opinion on pharmacotherapy, 2018 - Taylor & Francis
Introduction: Clostridium difficile infection (CDI) has become a significant healthcare-
associated infection and is strongly associated with antibiotic use. Practice guidelines have …

Advances in the treatment of Clostridium difficile with fidaxomicin: a narrow spectrum antibiotic

P Sears, Y Ichikawa, N Ruiz… - Annals of the New York …, 2013 - Wiley Online Library
Clostridium difficile infection, also known as C. difficile‐associated diarrhea (CDAD), is the
most common cause of nosocomial diarrhea, typically initiated by the use of broad‐spectrum …

Clostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions

VK Viswanathan, M Mallozzi, G Vedantam - Gut microbes, 2010 - Taylor & Francis
Clostridium difficile infection (CDI) is the primary cause of antibiotic-associated diarrhea, and
is a significant nosocomial disease. In the past ten years, variant toxin-producing strains of …

Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection

D Zhu, JA Sorg, X Sun - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an
important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form …