Fractional Ca2+ Currents through Capsaicin‐ and Proton‐Activated Ion Channels in Rat Dorsal Root Ganglion Neurones
HU Zeilhofer, M Kress… - The Journal of physiology, 1997 - Wiley Online Library
1 Capsaicin and protons cause excitation and sensitization of primary nociceptive afferents.
In a subset of dorsal root ganglion (DRG) neurones, which probably represent nociceptive …
In a subset of dorsal root ganglion (DRG) neurones, which probably represent nociceptive …
Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells
M Petersen, RH LaMotte - Pain, 1993 - Elsevier
Capsaicin excites a subset of dorsal root ganglion (DRG) neurons by inducing an inward
current. We have examined this inward current in response to high concentrations of protons …
current. We have examined this inward current in response to high concentrations of protons …
Rat dorsal root ganglion neurones express different capsaicin-evoked Ca2+ transients and permeabilities to Mn2+
VN Dedov, BD Roufogalis - Neuroscience letters, 1998 - Elsevier
Capsaicin (1 μM) evoked [Ca2+] i transients in two-thirds of a Percoll-gradient enriched
population of rat dorsal root ganglion (DRG) neurones. Amongst the capsaicin-sensitive …
population of rat dorsal root ganglion (DRG) neurones. Amongst the capsaicin-sensitive …
A study of the voltage dependence of capsaicin‐activated membrane currents in rat sensory neurones before and after acute desensitization
AS Piper, JC Yeats, S Bevan… - The Journal of …, 1999 - Wiley Online Library
1 Responses to capsaicin in isolated sensory neurones have been shown to desensitize in
a Ca2+‐and voltage‐dependent manner. We have studied desensitization of capsaicin …
a Ca2+‐and voltage‐dependent manner. We have studied desensitization of capsaicin …
Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
RJ Docherty, JC Yeats, S Bevan, H Boddeke - Pflügers Archiv, 1996 - Springer
Capsaicin activates a non-specific cation conductance in mammalian sensory neurones. If
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
Modulation of calcium-currents by capsaicin in a subpopulation of sensory neurones of guinea pig
M Petersen, G Wagner, FK Pierau - Naunyn-Schmiedeberg's archives of …, 1989 - Springer
The action of capsaicin (CAP) on the total Ca 2+ current was examined in internally perfused
voltage-clamped dorsal root ganglion (DRG) neurones of guinea pigs. CAP changed the …
voltage-clamped dorsal root ganglion (DRG) neurones of guinea pigs. CAP changed the …
Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult rat dorsal root ganglion neurons in culture
RJ Docherty, B Robertson, S Bevan - Neuroscience, 1991 - Elsevier
The effect of capsaicin on voltage-activated calcium currents was investigated in
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
The effect of capsaicin on voltage‐gated calcium currents and calcium signals in cultured dorsal root ganglion cells
D Bleakman, JR Brorson… - British journal of …, 1990 - Wiley Online Library
1 The effects of capsaicin on voltage‐gated Ca2+ currents (ICa), and intracellular Ca2+
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
[PDF][PDF] Extracellular protons both increase the activity and reduce the conductance of capsaicin-gated channels
TK Baumann, ME Martenson - The Journal of Neuroscience, 2000 - Soc Neuroscience
Capsaicin evokes a membrane current in trigeminal ganglion neurons that is increased
substantially in a moderately acidic extracellular environment. Using excised outside-out …
substantially in a moderately acidic extracellular environment. Using excised outside-out …
Ca2+ permeability of the sustained proton-induced cation current in adult rat dorsal root ganglion neurons
HU Zeilhofer, D Swandulla… - Journal of …, 1996 - journals.physiology.org
1. Microfluorometric Ca2+ measurements using FURA-2 and whole cell patch-clamp
recordings were performed to investigate the Ca2+ permeability of ion channels underlying …
recordings were performed to investigate the Ca2+ permeability of ion channels underlying …