For bioluminescence and fluorescence imaging studies in small animals, it is important to be
able to accurately estimate the 3D distribution of a light-emitting source within the animal …

An accurate knowledge of tissue optical properties (absorption coefficients, μ a, and reduced
scattering coefficients, μ s') is critical for precise modeling of light propagation in biological …

Herein we present a comparison of Monte Carlo, radiative transport (RT), and diffusion
based forward models for implementation into small animal optical tomography algorithm …

Optical phantoms with tissue-mimicking properties have long been recognized as an
important intermediary stage for developing metrological techniques, and their use in …

Detecting objects optically within human tissue is difficult because this medium scatters most
of the light that enters it, while absorbing very little. Optical Tomography (OT) is a method of …

Molecular probes used for in vivo optical fluorescence tomography (OFT) studies in small
animals are typically chosen such that their emission spectra lie in the 680–850 nm …

In near-infrared fluorescence molecular tomography (FMT), high turbidity of biological tissue
exerts severe adversity to image reconstruction. In contrast to highly diffusive photons, early …

Small animal imaging plays a critical role in present day biomedical research by filling an
important gap in the translation of research from the bench to the bedside. Optical …

A fully integrated trimodality fluorescence, diffuse optical, and x-ray computed tomography
(FT/DOT/XCT) system for small animal imaging is reported in this work. The main purpose of …

Multiple scattering is a major source that limits light penetration into biotissues, thereby
preventing visualization of the deep microstructures for high-resolution optical imaging …