A-to-I editing is an adenosine-to-inosine modification of mRNA particularly widespread in
the human brain, where it affects thousands of genes. A growing body of evidence suggests …

Adenosine to inosine (A-to-I) RNA editing, catalyzed by the ADAR enzyme family, acts on
dsRNA structures within pre-mRNA molecules. Editing of the coding part of the mRNA may …

RNA editing is a post-transcriptional process, which results in base substitution
modifications to RNA. It is an important process in generating protein diversity through …

A-to-I RNA editing is common in all eukaryotes, and is associated with various neurological
functions. Recently, A-to-I editing was found to occur frequently in the human transcriptome …

The post-transcriptional modification of mammalian transcripts by A-to-I RNA editing has
beenrecognized as an important mechanism for the generation of molecular diversity and …

Aging is a physiological and progressive phenomenon in all organisms' life cycle,
characterized by the accumulation of degenerative processes triggered by several …

Abstract Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA
modification within the brain. Yet, most research has relied on postmortem samples …

Background Adenosine-to-inosine (A-to-I) RNA editing, mediated by ADAR1 and ADAR2,
occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I …

Abstract A-to-I RNA editing is an important process for generating molecular diversity in the
brain through modification of transcripts encoding several proteins important for neuronal …

Abstract Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional processing event
involved in diversifying the transcriptome and is responsible for various biological …