Chondrocyte apoptosis: a cause or consequence of osteoarthritis?
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and changes in the subchondral bone. Over the last two decades, there has …
degradation and changes in the subchondral bone. Over the last two decades, there has …
Chondrocyte death by apoptosis is associated with the initiation and severity of articular cartilage degradation
CM Thomas, CJ Fuller, CE Whittles… - International journal of …, 2011 - Wiley Online Library
Aim: To investigate the role of chondrocyte apoptosis in the initiation and severity of articular
cartilage (AC) damage. Methods: Articular cartilage from equine metacarpophalangeal …
cartilage (AC) damage. Methods: Articular cartilage from equine metacarpophalangeal …
Apoptosis in osteoarthritis: morphology, mechanisms, and potential means for therapeutic intervention.
Osteoarthritis (OA) is the most common chronic joint disorder found in the aging population
and is primarily characterized by loss of articular cartilage. Because chondrocytes are …
and is primarily characterized by loss of articular cartilage. Because chondrocytes are …
Osteoarthritis chondrocytes die by apoptosis: a possible pathway for osteoarthritis pathology
FJ Blanco, R Guitian, E Vázquez‐Martul… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To determine which kind of cell death occurs in cartilage from patients with
osteoarthritis (OA). Methods Seven normal and 16 OA cartilage samples were collected at …
osteoarthritis (OA). Methods Seven normal and 16 OA cartilage samples were collected at …
Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase‐3
M Sharif, A Whitehouse, P Sharman… - … : Official Journal of …, 2004 - Wiley Online Library
Objective Chondrocyte apoptosis has been described in both human and experimentally
induced osteoarthritis (OA), but its importance in the etiopathogenesis of OA is uncertain …
induced osteoarthritis (OA), but its importance in the etiopathogenesis of OA is uncertain …
Chondrocyte death involvement in osteoarthritis
S Salucci, E Falcieri, M Battistelli - Cell and tissue research, 2022 - Springer
Chondrocyte apoptosis is known to contribute to articular cartilage damage in osteoarthritis
and is correlated to a number of cartilage disorders. Micromass cultures represent a …
and is correlated to a number of cartilage disorders. Micromass cultures represent a …
Chondrocyte apoptosis in the pathogenesis of osteoarthritis
HS Hwang, HA Kim - International journal of molecular sciences, 2015 - mdpi.com
Apoptosis is a highly-regulated, active process of cell death involved in development,
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …
Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
S Hashimoto, RL Ochs, S Komiya… - Arthritis & Rheumatism …, 1998 - Wiley Online Library
Objective To examine the occurrence of apoptosis in human osteoarthritis (OA) cartilage,
and to determine its relationship to cartilage degradation. Methods Knee cartilage was …
and to determine its relationship to cartilage degradation. Methods Knee cartilage was …
Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease
Osteoarthritis (OA) is the most common joint disease characterised by degradation of
articular cartilage and bone remodelling. For almost a decade chondrocyte apoptosis has …
articular cartilage and bone remodelling. For almost a decade chondrocyte apoptosis has …
Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritic human articular knee cartilage: a study of proliferation, programmed cell …
T Aigner, M Hemmel, D Neureiter… - … : official Journal of …, 2001 - Wiley Online Library
Objective Chondrocytes are crucial for adequate matrix balance and function. Cell
proliferation and, recently, extensive apoptotic cell death have been reported in …
proliferation and, recently, extensive apoptotic cell death have been reported in …