This study aimed to comparatively investigate the anti-tumor mechanisms of steroids
including ergosterol, β-sitosterol, cholesterol, and fucosterol. The model of H22 tumor …

Sterols are one of the main components of medicinal fungi with an anti-tumor effect. In this
study, ergosta-4, 6, 8 (14), 22-tetraen-3-one (ET) and (22E, 24R)-ergosta-7, 22-dien-3β, 5α …

In this review, steroids with a tertiary butyl group, which are usually called neo steroids, are a
small group of natural lipids isolated from higher plants, fungi, marine sponges, and yeast. In …

Four steroids, ergosterol (ergosta-5, 7, 22-triene-3β-ol), ergosterol peroxide (5α, 8α-
epidioxyergosta-6, 22-dien-3β-ol), ergosta-7, 22-dien-3β-yl palmitate and ergosta-4, 6, 8 …

Ergosterone has been proved to have potential antitumor effect on H22 tumor-bearing mice,
but the antitumor mechanism and key regulators are still unclear. The current study was …

Cancer is recognized as one of the most prevalent contributors to mortality in several nations
and it remains one of the common health issues globally. In particular, hepatocellular …

The present review describes biological activities of semi-and synthetic epithio steroids.
About fifty biologically active compounds have shown confirmed antitumor …

Research of steroidal compounds as anticancer agents started almost 50 years ago. During
the past decades, several innovative new steroids, like cyproterone, finasteride, estramustin …

Cancer continues to be a serious threat to human health worldwide. Lung, prostate and
triple-negative breast cancers are amongst the most incident and deadliest cancers …

Modification of steroid molecules by introducing heterocyclic ring into the core structure of
steroids has been utilized as an attractive approach for either cancer prognosis or diagnosis …