Using cholesterol as starting material, a series of 6-substituted-3-aza-A-homo-3-
oxycholestanes and 6-substituted-4-aza-A-homo-3-oxycholestanes were synthesized by the …

Steroids are polycyclic compounds that have a wide range of biological activities. They are
bio-synthesized from cholesterol through a series of enzyme-mediated transformations, so …

The present review article describes distribution and biological activities of steroids
containing a tertiary butyl group. More than 65 biological active steroids have shown …

Phytosterol is a natural component of vegetable oil and includes ergosterol (ER) and β-
sitosterol. In this study, three new ergosterol monoester derivatives were obtained from the …

Tumor-derived metabolites dampen tumor-infiltrating immune cells and antitumor immune
responses. Among the various metabolites produced by tumors, we recently showed that …

Using cholesterol as starting material, some steroidal lactone compounds with the structures
of 3-substituted-6-oxo-7-oxa-B-homo-cholestane or 3-substituted-7-oxo-6-oxa-B-homo …

In addition to being highly stable, estrogen is widely available in the environment, food, and
produce various metabolites such as 2-hydroxyestrone (2-OH-E1), 2-methoxyestrone (2 …

Background: Cancer is one of the leading causes of death around the world. It has potential
to spread and destroy the surrounding tissues. The most common cancer seen in men is …

Covering: up to 2012 Steroids, a widespread class of natural organic compounds occurring
in animals, plants and fungi, have shown great therapeutic value for a broad array of …

Ever since the description of estradiol (E2) by Doisy et al.(1930), steroid hormones have
been the object of almost continual attention of scientists working in different fields; it …