Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in …
FR429, an ellagitannin (a type of polyphenol), is isolated and purified from Polygonum
capitatum Buch.-Ham. ex D. Don which is the original herbal medicine of the “Re-Lin-Qing” …
capitatum Buch.-Ham. ex D. Don which is the original herbal medicine of the “Re-Lin-Qing” …
Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro
A Spalenkova, M Ehrlichova, S Wei… - The Journal of Steroid …, 2023 - Elsevier
Oxysterols play significant roles in many physiological and pathological processes including
cancer. They modulate some of the cancer hallmarks pathways, influence the efficacy of anti …
cancer. They modulate some of the cancer hallmarks pathways, influence the efficacy of anti …
[HTML][HTML] The proapoptotic effect of formononetin in human osteosarcoma cells: involvement of inactivation of ERK and Akt pathways
Y Liu, JJ He, XM Chen, J Li, MR Shen, WJ Yu… - Cellular Physiology and …, 2014 - karger.com
Background: Previous studies have shown that some phytoestrogens inhibits proliferation
and induces apoptosis in estrogen-dependent cancers via estrogen receptor (ER)-mediated …
and induces apoptosis in estrogen-dependent cancers via estrogen receptor (ER)-mediated …
Metabolic transformation of breast cancer in a MCF-7 xenograft mouse model and inhibitory effect of volatile oil from Saussurea lappa Decne treatment
Z Peng, Y Wang, X Gu, Y Xue, Q Wu, J Zhou, C Yan - Metabolomics, 2015 - Springer
Breast cancer results from multi-step carcinogenesis, and the transforming process from
normal to malignant cells is associated with profound metabolic disturbances. The metabolic …
normal to malignant cells is associated with profound metabolic disturbances. The metabolic …
Research on the mechanisms of taraxerol for the treatment of gastric cancer effect based on network pharmacology
B Huo, Y Song, B Tan, J Li, J Zhang… - International …, 2022 - journals.sagepub.com
Background: Modern pharmacological studies have shown that traditional Chinese
medicine (TCM) Taraxacum mongolicum possesses anti-cancer activity. Taraxerol (TRX) is …
medicine (TCM) Taraxacum mongolicum possesses anti-cancer activity. Taraxerol (TRX) is …
Oxysterols in catfish skin secretions (Arius bilineatus, Val.) exhibit anti-cancer properties
JM Al-Hassan, M Afzal, S Oommen, YF Liu… - Frontiers in …, 2022 - frontiersin.org
The edible catfish Arius bilineatus,(Valenciennes) elaborates a proteinaceous gel-like
material through its epidermis when threatened or injured. Our on-going studies on this gel …
material through its epidermis when threatened or injured. Our on-going studies on this gel …
[HTML][HTML] Metabonomics of mice intestine in Codonopsis foetens induced apoptosis of intestine cancer cells
Y Luan, Y Li, X Yue, Y Cao, F Xiang, D Mao… - Saudi Journal of …, 2019 - Elsevier
Intestinal cancer is a disease with high morbidity and high mortality in China. Previous
studies have shown that Codonopsis foetens can inhibit cellular autophagy and promote the …
studies have shown that Codonopsis foetens can inhibit cellular autophagy and promote the …
Main determinants affecting the antiproliferative activity of stilbenes and their Gut microbiota metabolites in colon cancer cells: A structure–activity relationship study
A González-Sarrías, JC Espín-Aguilar… - International Journal of …, 2022 - mdpi.com
trans-Resveratrol can be catabolized by the gut microbiota to dihydroresveratrol, 3, 4′-
dihydroxy-trans-stilbene, lunularin, and 4-hydroxydibenzyl. These metabolites can reach …
dihydroxy-trans-stilbene, lunularin, and 4-hydroxydibenzyl. These metabolites can reach …
Metabolomic study of corticosterone-induced cytotoxicity in PC12 cells by ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry
H Zhang, H Zheng, G Zhao, C Tang, S Lu… - Molecular …, 2016 - pubs.rsc.org
Glucocorticoids (GCs) have been proved to be an important pathogenic factor of some
neuropsychiatric disorders. Usually, a classical injury model based on corticosterone …
neuropsychiatric disorders. Usually, a classical injury model based on corticosterone …
[HTML][HTML] 3-β-Εrythrodiol isolated from Conyza canadensis inhibits MKN‑45 human gastric cancer cell proliferation by inducing apoptosis, cell cycle arrest, DNA …
The objective of the present study was to investigate the in vitro and in vivo anticancer and
apoptotic effects of 3-β-erythrodiol, a plant-derived triterpene against MKN-45 human gastric …
apoptotic effects of 3-β-erythrodiol, a plant-derived triterpene against MKN-45 human gastric …