[引用][C] Disposition of the herbicide atrazine and its major metabolites in mice: An LC-MS analysis of urine, plasma, and tissue levels

MK Ross, TL Jones, NM Filipov - Drug Metabolism and Disposition, 2008 - ASPET
Atrazine is a toxicologically-important and widely used herbicide. Recent studies have
demonstrated that it can elicit neurological, immunological, developmental, and biochemical …

Disposition of the herbicide 2-chloro-4-(ethylamino)-6-(isopropylamino)-s-triazine (Atrazine) and its major metabolites in mice: a liquid chromatography/mass …

MK Ross, TL Jones, NM Filipov - Drug Metabolism and Disposition, 2009 - ASPET
2-Chloro-4-(ethylamino)-6-(isopropylamino)-s-triazine (atrazine, ATR) is a toxicologically
important and widely used herbicide. Recent studies have shown that it can elicit …

Determination of atrazine and its metabolites in mouse urine and plasma by LC–MS analysis

MK Ross, NM Filipov - Analytical biochemistry, 2006 - Elsevier
Atrazine is a herbicide widely used on agricultural commodities. Existing analytical methods
to analyze atrazine and its metabolites in biological matrices have various drawbacks. Thus …

Pharmacokinetics of [14C]-atrazine in rhesus monkeys, single-dose intravenous and oral administration

X Hui, RC Wester, HI Maibach - Toxicological & Environmental …, 2011 - Taylor & Francis
This is the first study regarding the pharmacokinetics of [14C]-atrazine conducted with
rhesus monkeys. The animals received one dose (0.25 mg) intravenously (IV) or three doses …

Potential biomarkers for monitoring the toxicity of long-term exposure to atrazine in rat by metabonomic analysis

XF Zhang, CH Zhang, J Zheng, LX Li, TQ Geng… - Xenobiotica, 2018 - Taylor & Francis
Herbicide atrazine (ATR) poses harmful effects on human health. The purpose of this study
is to study potential biomarkers used for monitoring the toxic effects after chronic exposure to …

Two-dimensional high performance liquid chromatography separation and tandem mass spectrometry detection of atrazine and its metabolic and hydrolysis products …

Z Kuklenyik, P Panuwet, NK Jayatilaka, JL Pirkle… - … of Chromatography B, 2012 - Elsevier
Atrazine [6-chloro-N-ethyl-N′-(1-methylethyl)-1, 3, 5-triazine-2, 4-diamine] is the most
widely used herbicide in the United States. In recent years, there has been controversy …

Short-term oral atrazine exposure alters the plasma metabolome of male C57BL/6 mice and disrupts α-linolenate, tryptophan, tyrosine and other major metabolic …

Z Lin, JR Roede, C He, DP Jones, NM Filipov - Toxicology, 2014 - Elsevier
Overexposure to the commonly used herbicide atrazine (ATR) affects several organ
systems, including the brain. Previously, we demonstrated that short-term oral ATR exposure …

Quantitative identification of atrazine and its chlorinated metabolites in plasma

JM Brzezicki, ME Andersen… - Journal of analytical …, 2003 - academic.oup.com
The objective of this study was to develop an analytical method to detect and quantitate the
chlorotriazine herbicide atrazine (ATRA), and its chlorinated metabolites [desethylatrazine …

Short-term atrazine exposure causes behavioral deficits and disrupts monoaminergic systems in male C57BL/6 mice

Z Lin, CA Dodd, NM Filipov - Neurotoxicology and teratology, 2013 - Elsevier
Excessive exposure to the widely used herbicide atrazine (ATR) affects several organ
systems, including the brain, where neurochemical alterations reflective of dopamine (DA) …

[图书][B] Toxicological profile for atrazine

A Dorsey - 2003 - books.google.com
The primary purpose of this chapter is to provide public health officials, physicians,
toxicologists, and other interested individuals and groups with an overall perspective on the …