[HTML][HTML] Caffeine ameliorates hyperoxia-induced lung injury by protecting GCH1 function in neonatal rat pups
X Jing, YW Huang, J Jarzembowski, Y Shi… - Pediatric …, 2017 - nature.com
Background Bronchopulmonary dysplasia (BPD) is a major morbidity in premature infants,
and impaired angiogenesis is considered a major contributor to BPD. Early caffeine …
and impaired angiogenesis is considered a major contributor to BPD. Early caffeine …
[HTML][HTML] Caffeine is associated with improved alveolarization and angiogenesis in male mice following hyperoxia induced lung injury
Background Caffeine therapy for apnea of prematurity reduces the incidence of
bronchopulmonary dysplasia (BPD) in premature neonates. Several mechanisms, including …
bronchopulmonary dysplasia (BPD) in premature neonates. Several mechanisms, including …
[HTML][HTML] Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia
Background While additional oxygen supply is often required for the survival of very
premature infants in intensive care, this also brings an increasing risk of progressive lung …
premature infants in intensive care, this also brings an increasing risk of progressive lung …
Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury
RJ Teng, X Jing, T Michalkiewicz… - … of Physiology-Lung …, 2017 - journals.physiology.org
Rodent pups exposed to hyperoxia develop lung changes similar to bronchopulmonary
dysplasia (BPD) in extremely premature infants. Oxidative stress from hyperoxia can injure …
dysplasia (BPD) in extremely premature infants. Oxidative stress from hyperoxia can injure …
Caffeine prevents hyperoxia-induced functional and structural lung damage in preterm rabbits
T Nagatomo, J Jiménez, J Richter, S De Baere… - Neonatology, 2016 - karger.com
Background: Caffeine is a commonly used drug for apnea of prematurity. It may, however,
also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most …
also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most …
[HTML][HTML] Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway
S Chen, Q Wu, D Zhong, C Li, L Du - Respiratory Research, 2020 - Springer
Background Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in
premature infants and hyperoxia exposure is a major cause. In hyperoxic lung injury animal …
premature infants and hyperoxia exposure is a major cause. In hyperoxic lung injury animal …
Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro
Caffeine is used to prevent bronchopulmonary dysplasia (BPD) in premature neonates.
Hyperoxia contributes to the development of BPD, inhibits cell proliferation and decreases …
Hyperoxia contributes to the development of BPD, inhibits cell proliferation and decreases …
[HTML][HTML] Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in a hyperoxia-based mouse model of bronchopulmonary …
P Rath, C Nardiello, DE Surate Solaligue, R Agius… - Pediatric …, 2017 - nature.com
Background: Caffeine is widely used to manage apnea of prematurity, and reduces the
incidence of bronchopulmonary dysplasia (BPD). Deregulated transforming growth factor …
incidence of bronchopulmonary dysplasia (BPD). Deregulated transforming growth factor …
Prevention of oxygen‐induced inflammatory lung injury by caffeine in neonatal rats
S Endesfelder, E Strauß, I Bendix… - Oxidative medicine …, 2020 - Wiley Online Library
Background. Preterm birth implies an array of respiratory diseases including apnea of
prematurity and bronchopulmonary dysplasia (BPD). Caffeine has been introduced to treat …
prematurity and bronchopulmonary dysplasia (BPD). Caffeine has been introduced to treat …
Caffeine and bronchopulmonary dysplasia: Clinical benefits and the mechanisms involved
Y Yuan, Y Yang, X Lei, W Dong - Pediatric Pulmonology, 2022 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease that occurs during the
neonatal period and is commonly associated with prematurity. This condition results in a …
neonatal period and is commonly associated with prematurity. This condition results in a …