Environment‐induced relapse is a major concern in drug addiction because of the strong
associations formed between drug reward and environment. Cocaine‐conditioned place …

The development and maintenance of cocaine addiction depend heavily on learned reward-
environment associations that can induce drug-seeking behavior and relapse …

Exposure to drug-paired cues can trigger addicts to relapse into drug seeking. Although the
molecular mechanisms underlying cue-elicited cocaine seeking are incompletely …

Drugs of abuse regulate the transcription factor cAMP response element-binding protein
(CREB) in striatal regions, including the nucleus accumbens (NAc). To explore how …

Repeated association of drugs of abuse with context leads to long-lasting behavioral
responses that reflect reward-controlled learning and participate in the establishment of …

Learned associations are hypothesized to develop between drug effects and contextual
stimuli during repeated drug administration to produce context‐specific sensitization that is …

This study was done to determine whether social and environmental factors alter cocaine
reward and proteins implicated in mediating drug reward in rats during early adolescence …

Rodents learn to associate the rewarding effects of drugs with the environment in which they
are encountered and, subsequently, will display a conditioned place preference (CPP) for …

Previously, a learning-free measure was used to demonstrate that chronic food restriction
(FR) increases the reward magnitude of a wide range of abused drugs. Moreover, a variety …

Cocaine treatment paired with environmental cues establishes a conditioned place
preference (CPP) for that environment. After expression of this preference, rats show …