Polymorphisms of genes related to vitamin D metabolism and transportation and its relationship with the risk of osteoporosis: protocol for a multicentre prospective …

J Wang, B Shu, CG Li, XW Xie, D Liang, BL Chen… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Osteoporotic fracture is one of the most common causes of disability and a
major contributor to medical care costs in many regions of the world. The polymorphisms of …

Vitamin D receptor gene polymorphisms and the risk of multiple sclerosis: An updated meta-analysis

XL Chen, ML Zhang, L Zhu, ML Peng, FZ Liu… - Microbial …, 2017 - Elsevier
Background The association between vitamin D receptor (VDR) gene polymorphisms and
multiple sclerosis (MS) has been extensively studied, but results were controversial …

[PDF][PDF] Vitamin D receptor (VDR) genetic polymorphisms associated with intervertebral disc degeneration

VDR VDR - Journal of Genetics and Genomics, 2015 - researchgate.net
Intervertebral disc degeneration (IDD) is characterized by disc dehydration and herniation,
which is often associated with low back pain and lumbar radiculopathy due to nerve root …

[PDF][PDF] Vitamin d deficiency and rs731236 (Taq1) vitamin D receptor gene polymorphism as possible risk factors for rheumatoid arthritis and osteoarthritis

S Mahmoud, MF Atoum, HM Al-Hourani… - Acta Med …, 2018 - researchgate.net
Introduction: Epidemiological evidence indicates a significant association between vitamin D
deficiency and an increased incidence of autoimmune diseases. The role of vitamin D and …

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein …

HA Kresge, F Blostein, S Goleva… - Twin Research and …, 2024 - cambridge.org
While it is known that vitamin D deficiency is associated with adverse bone outcomes, it
remains unclear whether low vitamin D status may increase the risk of a wider range of …

The relationship between vitamin D receptor gene polymorphisms and ankylosing spondylitis: a systematic review, meta-analysis and trial sequential analysis

H Zhou, BY Zhou, SR Liang, M Li, J Zhao - Rheumatology International, 2023 - Springer
The relation between vitamin D receptor (VDR) gene polymorphisms and ankylosing
spondylitis (AS) remains unclear. A systematic review and meta-analysis were conducted …

[HTML][HTML] Genomic or non-genomic? A question about the pleiotropic roles of vitamin D in inflammatory-based diseases

MF Holick, L Mazzei, S García Menéndez… - Nutrients, 2023 - mdpi.com
Vitamin D (vit D) is widely known for its role in calcium metabolism and its importance for the
bone system. However, various studies have revealed a myriad of extra-skeletal functions …

Associations of Vitamin D Levels and Vitamin D Receptor Genotypes with Patient-Reported Outcome/Disease Activity in Patients with Rheumatoid Arthritis.

SO Khoja, Y El-Miedany, AP Iyer… - Clinical …, 2018 - search.ebscohost.com
Background: The aim of this study is to evaluate the prevalence of vitamin-D insufficiency
and vitamin-D receptor (VDR) polymorphisms in rheumatoid arthritis (RA) patients and its …

[引用][C] Vitamin D: The unexplored immunomodulator

BK Das, AK Panda - International Journal of Rheumatic …, 2016 - Wiley Online Library
In the year 1922, Elmer McCollum demonstrated cure of rickets in dogs by modified cod liver
oil and named it as vitamin D. Since then it was believed that the major functions of vitamin …

Association between vitamin D receptor gene polymorphism and vitamin D deficiency rickets

SH Wu, XD Yu, CH Yan, LX Shen, XG Yu… - … Dang dai er ke za zhi …, 2006 - europepmc.org
Objective To explore the genetic susceptibility of children to vitamin D deficiency rickets
through studying the association between Vitamin D receptor (VDR) gene polymorphism …