Anti-inflammatory effects of dietary vitamin D3 in patients with multiple sclerosis

R Hashemi, M Morshedi, M Asghari Jafarabadi… - Neurology …, 2018 - AAN Enterprises
Objective To assess the effects of dietary vitamin D3 on proinflammatory (interleukin-17A [IL-
17A] and IL-6) and anti-inflammatory (IL-10) cytokines. Methods Our study was conducted …

Effect of high dose vitamin D intake on interleukin-17 levels in multiple sclerosis: a randomized, double-blind, placebo-controlled clinical trial

N Toghianifar, F Ashtari, SH Zarkesh-Esfahani… - Journal of …, 2015 - Elsevier
Background Vitamin D has immunomodulatory effects in multiple sclerosis (MS). Vitamin D
acts through various mechanisms such as secretion of cytokines. Interleukin-17 (IL-17) is a …

Vitamin D supplementation up-regulates IL-6 and IL-17A gene expression in multiple sclerosis patients

BN Gargari, M Behmanesh, ZS Farsani… - International …, 2015 - Elsevier
Vitamin D regulates gene expression and affects target cell functions. IL-6 and IL-17A are
pro-inflammatory cytokines associated with MS pathogenesis. The aim of this study was to …

Short-term effect of high-dose vitamin D on the level of interleukin 10 in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled clinical trial

F Ashtari, N Toghianifar, SH Zarkesh-Esfahani… - …, 2015 - karger.com
Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the central
nervous system. Vitamin D has been related to the prevention of MS and to modulating its …

The impact of vitamin D3 intake on inflammatory markers in multiple sclerosis patients and their first-degree relatives

R Hashemi, SS Hosseini-Asl, SR Arefhosseini… - PloS one, 2020 - journals.plos.org
Background & aims In our previous study, a Seesaw model was proposed for the fluctuation
of crucial anti-(IL-10) and pro-inflammatory (Il-6 & IL-17A) cytokines through vitamin D3. In …

The impact of vitamin D low doses on its serum level and cytokine profile in multiple sclerosis patients

A Walawska-Hrycek, W Galus, E Hrycek… - Journal of Clinical …, 2021 - mdpi.com
Vitamin D is known to have immunomodulatory properties and its deficiency is identified as
an environmental risk factor for the development of autoimmune diseases, including multiple …

Vitamin D Supplementation: Effect on Cytokine Profile in Multiple Sclerosis

M Sparaco, S Bonavita - Journal of Clinical Medicine, 2024 - mdpi.com
Vitamin D is known for its role in modulating calcium and phosphate homeostasis and is
implicated both in bone mineralization and immune system regulation. The immune …

Vitamin D supplementation and systemic inflammation in relapsing-remitting multiple sclerosis

E Røsjø, LH Steffensen, L Jørgensen, JC Lindstrøm… - Journal of …, 2015 - Springer
Observational studies have suggested that vitamin D may reduce inflammation in relapsing-
remitting multiple sclerosis (RRMS), but this has not been clearly confirmed in randomized …

Interleukin-10 but not transforming growth factor-β1 gene expression is up-regulated by vitamin D treatment in multiple sclerosis patients

ZS Farsani, M Behmanesh, MA Sahraian - Journal of the Neurological …, 2015 - Elsevier
Multiple sclerosis (MS) is an inflammatory and autoimmune disease. Variety of different
genetics and environmental factors are involved in MS pathology. The epidemiological …

Therapeutic effect of vitamin D3 in multiple sclerosis patients

G Mosayebi, A Ghazavi, K Ghasami… - Immunological …, 2011 - Taylor & Francis
Multiple sclerosis (MS) is an inflammatory disease in which the myelin sheaths around the
axons of the central nervous system are damaged. The damage leads to demyelination and …