Nitrosative stress caused by reactive nitrogen species such as nitric oxide and peroxynitrite
overproduced during inflammation leads to cell death and has been implicated in the …

Recent reports devoted to the field of oxygen sensing outline that signalling molecules such
as nitric oxide/nitric oxide derived species as well as cytokines and other inflammatory …

In clinical settings, oxygen therapy is administered to preterm neonates and to adults with
acute and chronic conditions such as COVID-19, pulmonary fibrosis, sepsis, cardiac arrest …

Significance: A mismatch between energy supply and demand induces tissue hypoxia with
the potential to cause cell death and organ failure. Whenever arterial oxygen concentration …

Nitric oxide (NO) is produced by different isoforms of nitric oxide synthases (NOSs) and
operates as a mediator of important cell signaling pathways, such as the cGMP signaling …

Nitric oxide (NO) exhibits multiple biological actions through formation of various oxidized
intermediates derived from NO. Among them, nitrosothiol adducts (RS-NOs) with the …

Lung epithelial and endothelial cell death caused by pro‐oxidant insults is a cardinal feature
of acute lung injury/acute respiratory distress syndrome (ALI/ARDS) patients. The NF‐E2 …

Formation of nitric oxide and its derivative reactive nitrogen species during endotoxemia has
been implicated in the pathogenesis of the associated cardiovascular dysfunction. This …

Although NO has been postulated to play important roles in host defences, it is potentially
damaging for exposed cells, including for the macrophages producing the NO. Thus a …

Although mitochondria and the Nox family of NADPH oxidase are major sources of reactive
oxygen species (ROS) induced by external stimuli, there is limited information on their …