Metabolic engineering
G Stephanopoulos - Current Opinion in Biotechnology, 1994 - Elsevier
Metabolic engineering is not another form of classic manipulation of intermediary
metabolism; rather, it is the purposeful design of metabolic networks. The metabolic …
metabolism; rather, it is the purposeful design of metabolic networks. The metabolic …
A perspective of metabolic engineering strategies: moving up the systems hierarchy
T Bulter, JR Bernstein, JC Liao - Biotechnology and …, 2003 - Wiley Online Library
Metabolic engineering has been established as an important field in biotechnology. It
involves the analysis, design, and alteration of the stoichiometric network using …
involves the analysis, design, and alteration of the stoichiometric network using …
Design principles and operating principles: the yin and yang of optimal functioning
EO Voit - Mathematical biosciences, 2003 - Elsevier
Metabolic engineering has as a goal the improvement of yield of desired products from
microorganisms and cell lines. This goal has traditionally been approached with …
microorganisms and cell lines. This goal has traditionally been approached with …
Metabolic engineering: techniques for analysis of targets for genetic manipulations
J Nielsen - Biotechnology and bioengineering, 1998 - Wiley Online Library
Metabolic engineering has been defined as the purposeful modification of intermediary
metabolism using recombinant DNA techniques. With this definition metabolic engineering …
metabolism using recombinant DNA techniques. With this definition metabolic engineering …
The essence of metabolic engineering
Metabolic engineering is a new field with applications in the production of chemicals, fuels,
materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the …
materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the …
[HTML][HTML] Metabolic pathway engineering
Organisms can be engineered to produce a wide variety of compounds by either enhancing
endogenous metabolic pathways, or by introducing exogenous pathways that are either …
endogenous metabolic pathways, or by introducing exogenous pathways that are either …
Metabolic engineering—Integrating methodologies of molecular breeding and bioprocess systems engineering
H Shimizu - Journal of bioscience and bioengineering, 2002 - Elsevier
Metabolic engineering is an integrating methodology of analysis and synthesis for the
improvement of flux distribution of metabolic pathways in complicated bioprocesses, which …
improvement of flux distribution of metabolic pathways in complicated bioprocesses, which …
Metabolic engineering: principles and methodologies
Metabolic engineering is a new field with applications in the production of chemicals, fuels,
materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the …
materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the …
[图书][B] Pathway analysis and optimization in metabolic engineering
Facility in the targeted manipulation of the genetic and metabolic composition of organisms,
combined with unprecedented computational power, is forging a niche for a new …
combined with unprecedented computational power, is forging a niche for a new …
Metabolic design: how to engineer a living cell to desired metabolite concentrations and fluxes
A biotechnological aim of genetic engineering is to increase the intracellular concentration
or secretion of valuable compounds, while making the other concentrations and fluxes …
or secretion of valuable compounds, while making the other concentrations and fluxes …