[HTML][HTML] Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

FA Castelli, G Rosati, C Moguet, C Fuentes… - Analytical and …, 2022 - Springer
Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

[HTML][HTML] Concepts and controversies in evaluating vitamin K status in population-based studies

MK Shea, SL Booth - Nutrients, 2016 - mdpi.com
A better understanding of vitamin K's role in health and disease requires the assessment of
vitamin K nutritional status in population and clinical studies. This is primarily accomplished …

[HTML][HTML] Metabolomics in the identification of biomarkers of dietary intake

A O'Gorman, H Gibbons, L Brennan - Computational and structural …, 2013 - Elsevier
Traditional methods for assessing dietary exposure can be unreliable, with under reporting
one of the main problems. In an attempt to overcome such problems there is increasing …

Clinical analysis of vitamin B6: determination of pyridoxal 5′-phosphate and 4-pyridoxic acid in human serum by reversed-phase high-performance liquid …

ME Rybak, CM Pfeiffer - Analytical biochemistry, 2004 - Elsevier
A reversed-phase high-performance liquid chromatography (HPLC) method with
fluorometric detection was developed for the routine determination of pyridoxal 5 …

[HTML][HTML] Perspective: the high-folate–low-vitamin B-12 interaction is a novel cause of vitamin B-12 depletion with a specific etiology—a hypothesis

J Selhub, JW Miller, AM Troen, JB Mason… - Advances in …, 2022 - Elsevier
Vitamin B-12 is a water-soluble vitamin that plays important roles in intermediary
metabolism. Vitamin B-12 deficiency has many identifiable causes, including autoimmune …

[HTML][HTML] Low Plasma Vitamin B-6 Status Affects Metabolism through the Kynurenine Pathway in Cardiovascular Patients with Systemic Inflammation1–4

Ø Midttun, A Ulvik, ER Pedersen, M Ebbing, Ø Bleie… - The Journal of …, 2011 - Elsevier
It is unclear whether reduced plasma pyridoxal 5'-phosphate (PLP) during inflammation
reflects an altered distribution or increased requirement of vitamin B-6 that may impair …

Indicators for Assessing Folate and Vitamin B12 Status and for Monitoring the Efficacy of Intervention Strategies

R Green - Food and nutrition bulletin, 2008 - journals.sagepub.com
Deficiencies of folate or of vitamin B12 are widespread and constitute a major global burden
of morbidity affecting all age groups. Detecting or confirming the presence of folate or …

[HTML][HTML] Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey

AJ MacFarlane, LS Greene-Finestone, Y Shi - The American journal of …, 2011 - Elsevier
Background: Vitamin B-12 is an important cofactor required for nucleotide and amino acid
metabolism. Vitamin B-12 deficiency causes anemia and neurologic abnormalities—a cause …

[HTML][HTML] Vitamin B-6

PJ Stover, MS Field - Advances in Nutrition, 2015 - ncbi.nlm.nih.gov
Vitamin B-6 is a water-soluble vitamin first discovered as a factor that cured dermatitis in rats.
There are 6 forms of vitamin B-6 found in mammals. The naturally occurring forms of the …

Determination of vitamin B6 vitamers and pyridoxic acid in plasma: development and evaluation of a high-performance liquid chromatographic assay

MR Bisp, MV Bor, EM Heinsvig, MA Kall, E Nexø - Analytical biochemistry, 2002 - Elsevier
Marginal deficiency of vitamin B6 has recently been related to cardiovascular diseases.
Because of that there is an increasing interest in a suitable and reliable method for …