Combining cytotoxic and immune-mediated gene therapy to treat brain tumors

JF Curtin, GD King, M Candolfi… - Current topics in …, 2005 - ingentaconnect.com
Glioblastoma (GBM) is a type of intracranial brain tumor, for which there is no cure. In spite of
advances in surgery, chemotherapy and radiotherapy, patients die within a year of …

Gene therapy for brain cancer: combination therapies provide enhanced efficacy and safety

M Candolfi, KM Kroeger, A Muhammad… - Current gene …, 2009 - ingentaconnect.com
Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults. Despite
significant advances in treatment and intensive research, the prognosis for patients with …

[图书][B] Brain tumor immunotherapy

LM Liau, DP Becker, TF Cloughesy, DD Bigner - 2000 - books.google.com
An authoritative panel of researchers and clinicians critically reviews the entire field to
provide a comprehensive guide to modern brain tumor immunotherapy and thereby …

[HTML][HTML] Toward effective immunotherapy for the treatment of malignant brain tumors

DA Mitchell, JH Sampson - Neurotherapeutics, 2009 - Elsevier
The immunologic treatment of cancer has long been heralded as a targeted molecular
therapeutic with the promise of eradicating tumor cells with minimal damage to surrounding …

Gene therapy for brain tumors: basic developments and clinical implementation

H Assi, M Candolfi, G Baker, Y Mineharu… - Neuroscience …, 2012 - Elsevier
Glioblastoma multiforme (GBM) is the most common and deadliest of adult primary brain
tumors. Due to its invasive nature and sensitive location, complete resection remains …

The future of cancer immunotherapy for brain tumors: a collaborative workshop

CE Brown, S Bucktrout, LH Butterfield, O Futer… - Journal of translational …, 2022 - Springer
Harnessing the effector mechanisms of the immune system to combat brain tumors with
antigen specificity and memory has been in research and clinical testing for many years …

[图书][B] Handbook of brain tumor chemotherapy, molecular therapeutics, and immunotherapy

HB Newton - 2018 - books.google.com
Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy,
Second Edition, provides a comprehensive overview of the molecular methodologies in the …

[HTML][HTML] Engineering challenges for brain tumor immunotherapy

JG Lyon, N Mokarram, T Saxena, SL Carroll… - Advanced Drug Delivery …, 2017 - Elsevier
Malignant brain tumors represent one of the most devastating forms of cancer with abject
survival rates that have not changed in the past 60 years. This is partly because the brain is …

Introduction to immunotherapy for brain tumor patients: challenges and future perspectives

ML Montoya, N Kasahara, H Okada - Neuro-oncology practice, 2020 - academic.oup.com
Malignant gliomas, including glioblastoma (GBM) as the most aggressive type of adult CNS
tumors, are notoriously resistant to current standard of care treatments, including surgery …

Immunotherapy for brain tumors

JH Sampson, MV Maus, CH June - Journal of Clinical Oncology, 2017 - ascopubs.org
Glioblastoma (GBM) is the most lethal form of brain tumor and remains a large, unmet
medical need. This review focuses on recent advances in the neurosciences that converge …