Extended spectrum β-lactamase producing enterobacteriaceae: carbapenem sparing options

AT Aslan, M Akova - Expert review of anti-infective therapy, 2019 - Taylor & Francis
Introduction: Carbapenems have an important place in our antibiotic armamentarium and
have been trusted to effectively treat infections caused by ESBL-producing …

[HTML][HTML] Current options for the treatment of infections due to extended-spectrum beta-lactamase-producing Enterobacteriaceae in different groups of patients

B Gutiérrez-Gutiérrez, J Rodríguez-Baño - Clinical Microbiology and …, 2019 - Elsevier
Background Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are a
frequent cause of invasive infections worldwide. Carbapenems are nowadays the most used …

The times they are a-changin': carbapenems for extended-spectrum-β-lactamase-producing bacteria

J Rodríguez-Baño - Antimicrobial Agents and Chemotherapy, 2015 - Am Soc Microbiol
Several antimicrobial agents are being investigated as alternatives to carbapenems in the
treatment of infections caused by ESBL-producing Enterobacteriaceae, which may be useful …

The use of noncarbapenem β-lactams for the treatment of extended-spectrum β-lactamase infections

PD Tamma, J Rodriguez-Baňo - Clinical Infectious Diseases, 2017 - academic.oup.com
The continued rise in infections caused by extended-spectrum β-lactamase (ESBL)–
producing pathogens is recognized globally as one of the most pressing concerns facing the …

Optimizing therapy for infections caused by Enterobacteriaceae producing extended-spectrum β-lactamases

A Endimiani, DL Paterson - Seminars in respiratory and critical …, 2007 - thieme-connect.com
The spread of multidrug-resistant Enterobacteriaceae is complicating the treatment of
nosocomial infections. In many parts of the world, resistance to third-generation …

Carbapenems versus alternative antibiotics for the treatment of bacteraemia due to Enterobacteriaceae producing extended-spectrum β-lactamases: a systematic …

KZ Vardakas, GS Tansarli, PI Rafailidis… - Journal of …, 2012 - academic.oup.com
Objectives To study the comparative mortality associated with carbapenems and alternative
antibiotics for the treatment of patients with extended-spectrum β-lactamase (ESBL)-positive …

Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria

RG D'Angelo, JK Johnson, JT Bork… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Extended spectrum β-lactamases (ESBL) and AmpC β-lactamases are
increasing causes of resistance in many Gram-negative pathogens of common infections …

Management of infections caused by extended-spectrum β–lactamase-producing Enterobacteriaceae: current evidence and future prospects

CC Sheu, SY Lin, YT Chang, CY Lee… - Expert Review of Anti …, 2018 - Taylor & Francis
Introduction: The spread of extended-spectrum β–lactamase (ESBL)-producing
Enterobacteriaceae has become a major public health threat worldwide. Area covered: A …

Which non-carbapenem antibiotics are active against extended-spectrum β-lactamase-producing Enterobacteriaceae?

H Bouxom, D Fournier, K Bouiller, D Hocquet… - International journal of …, 2018 - Elsevier
In this study, the activity of 18 non-carbapenem antibiotics was evaluated against 100
extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (ESBL-Ec) and 50 ESBL …

Alternatives to carbapenems for infections caused by ESBL-producing Enterobacteriaceae

B Pilmis, P Parize, JR Zahar, O Lortholary - European journal of clinical …, 2014 - Springer
Since 2006, extended-spectrum beta-lactamase (ESBL)-producing isolates have spread in
France, as well as elsewhere [1–3]. As these isolates are often multidrug-resistant …