The role of mitochondrial function in the oocyte and embryo

R Dumollard, M Duchen, J Carroll - Current topics in developmental …, 2007 - Elsevier
Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells

J Van Blerkom - Reproductive biomedicine online, 2008 - Elsevier
In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

Embryo and its mitochondria

P May-Panloup, M Boguenet, H El Hachem, PE Bouet… - Antioxidants, 2021 - mdpi.com
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

Mitochondria in early mammalian development

J Van Blerkom - Seminars in cell & developmental biology, 2009 - Elsevier
The role of mitochondria as central determinants of development competence of oocytes
and preimplantation stage embryos is considered in the context of the diverse activities …

Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence

J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …

Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells

J Ramalho-Santos, S Varum, S Amaral… - Human reproduction …, 2009 - academic.oup.com
BACKGROUND Mitochondria are multitasking organelles involved in ATP synthesis,
reactive oxygen species (ROS) production, calcium signalling and apoptosis; and …

Mitochondrial function and redox state in mammalian embryos

R Dumollard, J Carroll, MR Duchen, K Campbell… - Seminars in cell & …, 2009 - Elsevier
Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

The role of maternal mitochondria during oogenesis, fertilization and embryogenesis

JM Cummins - Reproductive BioMedicine Online, 2002 - Elsevier
This review examines the place of mitochondria in the life cycle through oogenesis,
ovulation and early embryogenesis. Mitochondria are semi-autonomous organelles …

Mitochondrial distribution and function in oocytes and early embryos

BD Bavister, JM Squirrell - Human Reproduction, 2000 - academic.oup.com
Active mitochondria relocate during oocyte maturation or fertilization in several species.
Detailed studies with hamster oocytes and early embryos reveal a pattern of active …