The development of analytical tools for the characterization of large biomolecules is an
emerging and rapidly evolving area. This development activity is motivated largely by the …

Healthcare systems worldwide are struggling to find ways to fund the cost of innovative
treatments such as gene therapies, regenerative medicine, and monoclonal antibodies …

The annual “LabEx MAbImprove industrial workshops” are primarily intended to provide
scientists involved in therapeutic antibodies, a comprehensive view about topics of interest …

There is a growing demand in the biopharmaceutical industry for high-throughput, large-
scale N-glycosylation profiling of therapeutic antibodies in all phases of product …

In this work, we utilize capillary electrophoresis–mass spectrometry (CE–MS) in an
integrated microfluidic platform to analyze an intact, lysine-linked antibody drug conjugate …

During the development of recombinant monoclonal antibody (rMAb) drugs, glycosylation
receives particular focus because changes in the attached glycans can have a significant …

In recent years, biotechnologically-derived drugs have been a major focus of research and
development in the pharmaceutical industry. Their pharmacokinetics and pharmacokinetic …

Correspondence to: Alain Beck; Email: alain. beck@ pierre-fabre. com Submitted: 01/11/10;
Accepted: 01/11/11 DOI: 10.4161/mabs. 3.2. 14785 in a sometimes confusing way. 4 To …

Antibody-based therapeutics constitute a major growth area in medicine today. However,
antibodies as drugs present significant analytical challenges as they are large, complex and …

As research, development, and manufacturing of biosimilar protein therapeutics proliferates,
there is great interest in the continued development of a portfolio of complementary …