An increasing number of patients suffering from renal diseases and limitations in standard
diagnostic and therapeutic approaches has created an intense interest in applying …

The tools of functional genomics and proteomics have provided us with promising novel
biomarkers for acute kidney injury and chronic kidney disease. It will be important in future …

Acute renal failure (ARF) as well as chronic kidney disease (CKD) are currently categorized
according to serum creatinine concentrations. Serum creatinine, however, has shortcomings …

Introduction: Kidney dysfunction poses a high burden on patients and health care systems.
Early detection and accurate prediction of kidney disease progression remains a major …

Acute kidney injury (AKI) is an increasingly frequent clinical condition that occurs in 5% of all
hospitalizations, and in up to 26% of critically ill patients [1]. AKI is associated with significant …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

The World Health Organization has estimated mortality and burden of chronic kidney
disease (CKD) in 2002 and predicted it will rank 13th in 2030 instead of 17th in 2002 among …

Acute Kidney Injury (AKI) is currently recognized as a life-threatening disease, leading to an
exponential increase in morbidity and mortality worldwide. At present, AKI is characterized …

Proteomics-based approaches are generating considerable data in clinical nephrology
covering almost all aspects of the discipline. Proteomic experiments commonly involve …