Somatostatin was first identified as a hypothalamic factor which inhibits the release of growth
hormone from the anterior pituitary (somatotropin release inhibitory factor, SRIF). Both SRIF …

I. Introduction S OMATOSTATIN [somatotropin release-inhibiting factor (SRIF)] is a 14-amino
acid polypeptide that is widely distributed throughout the central nervous system and …

The distribution and density of SRIF receptors (SRIF‐R) were studied during development in
the rat somatosensory cortex by in vitro autoradiography with monoiodinated [Tyr0‐DTrp8] …

Somatostatin (SST) or somatotropin release-inhibiting factor (SRIF) was first discovered in
hypothalamic extracts as an activity that inhibited growth hormone secretion from cultured …

The peptide somatostatin (SST) is widely synthesized in the brain and periphery and acts
through a family of five receptors (SSTR1-5) to exert numerous effects. A gene product …

Somatostatin (SST) inhibits the secretion of many peptide hormones including growth
hormone (GH). The various functions of SST are mediated through at least five different …

Somatostatin (SRIF) exerts diverse physiological actions in the body including regulation of
hormone and neurotransmitter release and neuronal firing activity. Analogs of SRIF are used …

Somatostatin (SRIF) is the main inhibitory peptide regulating growth hormone (GH)
secretion. It has been difficult to establish the role of endogenous SRIF release in the …

Somatostatin is a cyclic peptide well known for its strong regulatory effects throughout the
body. Also known by the name of growth hormone inhibiting hormone, it is produced in …

Somatostatin (somatotropin release inhibitory factor, SRIF) and the related cortistatin (CST)
are multifunctional peptide molecules attributed with neurohormone, neurotransmitter …