Somatostatin (SOM) was originally isolated as the hypothalamic inhibitor of growth hormone
release but was subsequently shown to have a widespread distribution including the …

The primary gene transcript of the mouse somatostatin receptor 2 is alternatively spliced
giving rise to two isoforms (mSSTR2A and mSSTR2B) which differ at the C-terminus. Using …

The recent molecular cloning of the genes and cDNAs encoding multiple somatostatin(SRIF)
receptor subtypes has allowed for the individual expression of these receptors in …

Abstract Somatostatin‐14 (SRIF) co‐localizes with γ‐aminobutyric acid (GABA) in the
hippocampus and regulates neuronal excitability. A role of SRIF in the control of seizures …

The somatostatins are neuropeptides of 14 and 28 amino acids that inhibit the release of
growth hormone and other hypophyseal and gastrointestinal peptides. These neuropeptides …

Abstract Treatment of hypothalamic cells in monolayer culture with transforming growth
factor-β1 (TGFβ1) significantly reduced both basal and cAMP-induced somatostatin …

The neuropeptide somatostatin is widely distributed in the CNS and is believed to play a role
as a neurotransmitter or a neuromodulator. Somatostatin mediates its actions by the binding …

The involvement of striatal somatostatin receptors (sst 1, sst 2 and sst 4) in locomotor activity
was investigated. Male Sprague–Dawley rats, 280–350 g, received in the striatum bilateral …

We have used an expression-cloning strategy to isolate a cDNA encoding a somatostatin
(somatotropin release-inhibiting factor, SRIF) receptor from rat cortex and hippocampus. A …

The tissue distribution of mRNA encoding five somatostatin receptor subtypes, SSTR1,
SSTR2, SSTR3, SSTR4, and SSTR5, was determined in adult rat tissues by solution …