Emerging function and potential diagnostic value of circular RNAs in cancer

X Cui, J Wang, Z Guo, M Li, M Li, S Liu, H Liu, W Li… - Molecular cancer, 2018 - Springer
As a novel class of endogenous RNAs, circRNAs, have a covalently closed continuous loop,
with neither a 5'to 3'polarity, nor a polyadenylated tail. Numerous circRNAs have been …

[HTML][HTML] An emerging function of circRNA-miRNAs-mRNA axis in human diseases

D Rong, H Sun, Z Li, S Liu, C Dong, K Fu, W Tang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a novel class of long noncoding RNAs, are characterized by a
covalently closed continuous loop without 5′ or 3′ polarities structure and have been …

Circular RNAs as biomarkers and therapeutic targets in cancer

A Beilerli, I Gareev, O Beylerli, G Yang, V Pavlov… - Seminars in cancer …, 2022 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed non-coding RNA molecules
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …

Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

Circular RNA in cancer development and immune regulation

W Li, JQ Liu, M Chen, J Xu… - Journal of cellular and …, 2022 - Wiley Online Library
Circular RNAs (circRNAs) are a class of single‐stranded RNAs with closed loop structures
formed by covalent bonds of head and tail. Exploration of circRNAs is continually increasing; …

Circles reshaping the RNA world: from waste to treasure

J Liu, T Liu, X Wang, A He - Molecular cancer, 2017 - Springer
A new type of RNAs was identified from genes traditionally thought to express messenger or
linear ncRNA (noncoding RNA) only. They were subsequently named as circRNAs (circular …

Recent research progress on circular RNAs: Biogenesis, properties, functions, and therapeutic potential

AR Sharma, M Bhattacharya, S Bhakta, A Saha… - … Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), an emerging family member of RNAs, have gained importance in
research due to their new functional roles in cellular physiology and disease progression …

[HTML][HTML] The biogenesis, function and clinical significance of circular RNAs in breast cancer

Y Zeng, Y Zou, G Gao, S Zheng, S Wu… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are noncoding RNAs that form covalently closed loop structures.
CircRNAs are dysregulated in cancer and play key roles in tumorigenesis, diagnosis, and …

[HTML][HTML] Circular RNAs in cancer: limitations in functional studies and diagnostic potential

F Li, Q Yang, AT He, BB Yang - Seminars in cancer biology, 2021 - Elsevier
Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …

Advances in circular RNAs and their roles in breast Cancer

X Wang, L Fang - Journal of Experimental & Clinical Cancer Research, 2018 - Springer
Circular RNAs (circRNAs) are a type of noncoding RNAs with a closed loop structure. With
the development of high-throughput sequencing, massive circRNAs have been discovered …