Specific expression and functions of circular RNAs

S Misir, N Wu, BB Yang - Cell Death & Differentiation, 2022 - nature.com
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …

Circular RNA in disease: Basic properties and biomedical relevance

X Chen, M Zhou, L Yant… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Circular RNAs (circRNAs) represent a class of covalently closed RNA molecules with great
diversity in molecular features, functions, and regulatory mechanisms. Emerging advances …

Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

Circular RNA in colorectal cancer

T Li, WC Wang, V McAlister, Q Zhou… - Journal of cellular and …, 2021 - Wiley Online Library
Circular RNA (circRNA) is a highly abundant type of single‐stranded non‐coding RNA.
Novel research has discovered many roles of circRNA in colorectal cancer (CRC) including …

[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer

X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …

[HTML][HTML] Circular RNAs: new layer of complexity evading breast cancer heterogeneity

A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …

Functions and clinical significance of circular RNAs in glioma

J Sun, B Li, C Shu, Q Ma, J Wang - Molecular cancer, 2020 - Springer
CircRNAs are a class of single-stranded RNA molecules with a covalently closed loop
structure and have been characterized by high stability, abundance, conservation, and …

Circular RNAs in cell cycle regulation: Mechanisms to clinical significance

W Xiao, J Li, J Hu, L Wang, JR Huang, G Sethi… - Cell …, 2021 - Wiley Online Library
Circular RNAs (circRNAs), a type of non‐coding RNA, are single‐stranded circularized
molecules characterized by high abundance, evolutionary conservation and cell …

Circular RNA—Is the Circle Perfect?

L Caba, L Florea, C Gug, DC Dimitriu, EV Gorduza - Biomolecules, 2021 - mdpi.com
Circular RNA (circRNA) is a distinct class of non-coding RNA produced, in principle, using a
back-splicing mechanism, conserved during evolution, with increased stability and a tissue …

[HTML][HTML] Circular RNA in pancreatic cancer: a novel avenue for the roles of diagnosis and treatment

Z Rong, J Xu, S Shi, Z Tan, Q Meng, J Hua, J Liu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC), an important cause of cancer-related deaths worldwide, is one of
the most malignant cancers characterized by a dismal prognosis. Circular RNAs (circRNAs) …