[HTML][HTML] Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs: A literature review
MM Sampaio, MLC Santos, HS Marques… - World journal of …, 2021 - ncbi.nlm.nih.gov
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm and was the first
neoplastic disease associated with a well-defined genotypic anomaly―the presence of the …
neoplastic disease associated with a well-defined genotypic anomaly―the presence of the …
Chronic myeloid leukemia in the era of tyrosine kinase inhibitors: an evolving paradigm of molecularly targeted therapy
MAM Ali - Molecular diagnosis & therapy, 2016 - Springer
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm, characterized by the
unrestrained expansion of pluripotent hematopoietic stem cells. CML was the first …
unrestrained expansion of pluripotent hematopoietic stem cells. CML was the first …
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review
X An, AK Tiwari, Y Sun, PR Ding, CR Ashby Jr… - Leukemia research, 2010 - Elsevier
Chronic Myeloid Leukemia (CML) is a clonal disease characterized by the presence of the
Philadelphia (Ph+) chromosome and its oncogenic product, BCR-ABL, a constitutively active …
Philadelphia (Ph+) chromosome and its oncogenic product, BCR-ABL, a constitutively active …
Chronic myeloid leukemia: beyond BCR-ABL1
T Zhou, LJ Medeiros, S Hu - Current hematologic malignancy reports, 2018 - Springer
Purpose of review In this review, we emphasize up-to-date practical cytogenetic and
molecular aspects of chronic myeloid leukemia (CML) and summarize current knowledge on …
molecular aspects of chronic myeloid leukemia (CML) and summarize current knowledge on …
Chronic Myeloid Leukemia: Modern therapies, current challenges and future directions
AEG Osman, MW Deininger - Blood reviews, 2021 - Elsevier
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a reciprocal
translocation [t (9; 22)(q34; q11. 2)] that leads to the fusion of ABL1 gene sequences (9q34) …
translocation [t (9; 22)(q34; q11. 2)] that leads to the fusion of ABL1 gene sequences (9q34) …
Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management
E Jabbour, H Kantarjian - American journal of hematology, 2012 - Wiley Online Library
Abstract Disease overview: Chronic Myeloid Leukemia (CML) is a myeloproliferative
neoplasm with an incidence of one–two cases per 100,000 adults and accounts for∼ 15 …
neoplasm with an incidence of one–two cases per 100,000 adults and accounts for∼ 15 …
Long‐term outcomes in the second‐line treatment of chronic myeloid leukemia: a review of tyrosine kinase inhibitors
E Jabbour, J Cortes, H Kantarjian - Cancer, 2011 - Wiley Online Library
Chronic myeloid leukemia (CML) is a progressive and often fatal myeloproliferative
neoplasm. The hallmark of CML is an acquired chromosomal translocation known as the …
neoplasm. The hallmark of CML is an acquired chromosomal translocation known as the …
Chronic myeloid leukemia
H Kantarjian, J Cortes, E Jabbour… - Molecular …, 2019 - Wiley Online Library
This chapter summarizes the knowledge regarding the molecular biology of chronic myeloid
leukemia (CML) and the treatment modalities, including novel breakpoint cluster region‐v …
leukemia (CML) and the treatment modalities, including novel breakpoint cluster region‐v …
The biology of chronic myelogenous leukemia: implications for imatinib therapy
RH Alvarez, H Kantarjian, JE Cortes - Seminars in hematology, 2007 - Elsevier
Chronic myelogenous leukemia (CML) results from the neoplastic transformation of primitive
hematopoietic stem cells, and has been classified as a myeloproliferative disorder. The …
hematopoietic stem cells, and has been classified as a myeloproliferative disorder. The …
Targeted drugs in chronic myeloid leukemia
J Gora-Tybor, T Robak - Current medicinal chemistry, 2008 - ingentaconnect.com
Chronic myeloid leukemia (CML) is characterized by the presence of the Philadelphia (Ph)
chromosome, which results from a reciprocal translocation between the long arms of the …
chromosome, which results from a reciprocal translocation between the long arms of the …