In this paper, we investigate the dynamics and optimal control of a combination therapy
model of glioma with adenoviruses and MEK inhibitors. We provide a theoretical study of the …

Oncolytic viruses are genetically engineered to treat growing tumours and represent a very
promising therapeutic strategy. Using a Gompertz growth law, we discuss a model that …

The paper uses nine coupled ordinary differential equations (ODEs) to describe a tumor-
immune competitive system. The model is then reduced to four nonlinear coupled ODEs …

Oncolytic virotherapy is an emerging treatment modality which uses replication-competent
viruses to destroy cancers without causing harm to normal tissues. By the development of …

In this paper a mathematical model describing the growth of a solid tumour in the presence
of an immune system response is presented. In particular, attention is focused upon the …

Over the last few decades, there have been significant developments in theoretical,
experimental, and clinical approaches to understand the dynamics of cancer cells and their …

This paper is devoted to exploring the effects of non-Gaussian fluctuations on dynamical
evolution of a tumor growth model with immunization, subject to non-Gaussian {\alpha} …

Abstract Adoptive Cell Transfer therapy of cancer is currently in full development and
mathematical modeling is playing a critical role in this area. We study a stochastic model …

New cancer treatment modalities that limit patient discomfort need to be developed. One
possible new therapy is the use of oncolytic (cancer-killing) viruses. It is only recently that …

In the last few decades, the dynamics of tumor cells and their growths are presented via
clinical, experimental, and theoretical approaches, which leads to the development of the …