Breast cancer is the second leading cause of cancer mortality among women. Given its
important role in DNA methylation and synthesis, one-carbon metabolism may affect breast …

Accumulating evidence from epidemiologic studies suggests that risk of breast cancer is
reduced in relation to increased consumption of folate and related B vitamins. We …

Purpose We examined the association of plasma B-vitamins and metabolites, and related
genetic variants, with risk of breast cancer among predominantly premenopausal women …

Environmental exposures and/or genetic background in Japanese population, which might
contribute to the relatively low breast cancer incidence rates in Japan, have not been …

Background: B vitamins, including vitamin B 6, are coenzymes that are important for DNA
integrity and stability. Deficiencies in B vitamins may promote tumor carcinogenesis …

Abstract Introduction The C677T polymorphism of the methylenetetrahydrofolate reductase
(MTHFR) gene has been hypothesized to increase breast cancer risk. However, results have …

We investigated the association between dietary intake of folate, vitamin B6, and the 5, 10-
methylenetetrahydrofolate reductase (MTHFR) genotype with breast cancer. A matched …

Folate, vitamin B6, vitamin B12, methionine, choline, and betaine are nutrients involved in
one-carbon metabolism and have been hypothesized to reduce the risk of breast cancer …

Background Vitamins involved in one-carbon metabolism are hypothesized to influence
breast cancer (BC) risk. However, epidemiologic studies that examined associations …

Background Several studies have determined that dietary intake of B vitamins may be
associated with breast cancer risk as a result of interactions between 5, 10 …