We conducted a hospital-based case-control study to investigate the associations of dietary
intake of folate and MTHFR C677T and A1298C polymorphisms with breast cancer in a …

In view of growing body of evidence substantiating the role of aberrations in one-carbon
metabolism in the pathophysiology of breast cancer and lack of studies on gene–gene …

Evidence is growing that low folate status may be a factor in the aetiology of several cancers,
including breast cancer. The methylenetetrahydrofolate reductase gene (MTHFR), which …

Single-nucleotide polymorphisms (SNPs) within genes of the one-carbon metabolism
pathway have been shown to interact with dietary folate intake to modify breast cancer (BC) …

Objective: we conducted a case-control study to investigate the association between dietary
folate, vitamin B 6 and vitamin B 12 intake, MTHFR and MTR genotype, and breast cancer …

Background: B vitamins such as folate, vitamin B-6, and vitamin B-12 are coenzymes that
are important for DNA integrity and stability. Deficiency in these B vitamins may promote …

Few studies have explored the associations of thiamin, niacin and riboflavin with risk of
cancer despite their role in potentially cancer-associated one-carbon metabolism. Using …

Objective: The influence of the vitamins A, C, and E on breast cancer development has not
been clarified. An effect of a vitamin per se implicates similar patterns for the effects of the …

Intakes of vitamins A, C, and E, folate, and carotenoids have been hypothesized to reduce
the risk of breast cancer. However, previous epidemiological studies on these nutrients and …

Background An accumulating body of evidence suggests that there is an inverse
relationship between the intake of folate (a water-soluble B-vitamin) and the risk of …