Previous studies demonstrated that penta-acetyl geniposide ((Ac) 5 GP, an acetylated
derivative of geniposide) exhibited better pharmacological functions than geniposide. This …

Background Osteoarthritis (OA) treatment aims to improve inflammation and delay cartilage
degeneration. However, there is no effective strategy presently available. Ononin, a …

The anti-inflammatory mechanism of lucidone isolated from the fruits of Lindera erythrocarpa
Makino was investigated. Our data indicate that lucidone significantly inhibits the production …

Moutan Cortex has been widely used to treat various types of arthritis in traditional Chinese
medicine. Paeonol is isolated as an active ingredient from Moutan Cortex. However, the …

Berberine (BBR) is a traditional folk medicine with excellent anti-inflammatory properties.
This study aimed to investigate the anti-arthritic effects of BBR in adjuvant arthritis (AA) in …

The present study was carried out to investigate the anti-arthritic activity of Berberis aristata
hydroalcoholic extract (BAHE) in formaldehyde-induced arthritis and adjuvant-induced …

Objective Previous clinical studies have found that total flavonoids of Rhizoma Drynariae
(TFRD) have a good therapeutic effect on osteoarthritis (OA), but its therapeutic mechanism …

Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …

The overproduction of MMPs (matrix metalloproteinases) and members of the ADAMTS (a
disintegrin and metalloproteinase with thrombospondin motifs) protein family plays an …

Pharmacological relevance Indirubin (IR) is a key active ingredient in the traditional Chinese
medication QingDai, also called indigo naturalis, which are extensively used in China to …