Use of the ion PGM and the genereader NGS systems in daily routine practice for advanced lung adenocarcinoma patients: A practical point of view reporting a …

S Heeke, V Hofman, E Long-Mira, V Lespinet, S Lalvée… - Cancers, 2018 - mdpi.com
Background: With the integration of various targeted therapies into the clinical management
of patients with advanced lung adenocarcinoma, next-generation sequencing (NGS) has …

Targeted gene next-generation sequencing panel in patients with advanced lung adenocarcinoma: paving the way for clinical implementation

MGO Fernandes, M Jacob, N Martins, CS Moura… - Cancers, 2019 - mdpi.com
Identification of targetable molecular changes is essential for selecting appropriate treatment
in patients with advanced lung adenocarcinoma. Methods: In this study, a Sanger …

Assessment of the clinical application of detecting EGFR, KRAS, PIK3CA and BRAF mutations in patients with non-small cell lung cancer using next-generation …

X Xu, Y Yang, H Li, Z Chen, G Jiang… - Scandinavian journal of …, 2016 - Taylor & Francis
Background: Next-generation sequencing (NGS) has been widely applied in clinical
research, while its application in routine clinical molecular testing requires careful validation …

Comparison of sequential testing and next generation sequencing in advanced lung adenocarcinoma patients–a single centre experience

FG Dall'Olio, N Conci, G Rossi, M Fiorentino… - Lung Cancer, 2020 - Elsevier
Objectives Molecular diagnosis determines therapeutic strategies for patients with non-small-
cell lung cancer–adenocarcinoma (NSCLC-A) but depends on resources availability. We …

[HTML][HTML] Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS …

CM de Las Casas, M Garzón-Ibañez… - Translational Cancer …, 2019 - ncbi.nlm.nih.gov
Background In a significant percentage of advanced non-small cell lung cancer (NSCLC)
patients, tumor tissue is unavailable or insufficient for genetic analyses at time to …

Next-generation sequencing for molecular diagnosis of lung adenocarcinoma specimens obtained by fine needle aspiration cytology

T Qiu, H Guo, H Zhao, L Wang, Z Zhang - Scientific reports, 2015 - nature.com
Identification of multi-gene variations has led to the development of new targeted therapies
in lung adenocarcinoma patients and identification of an appropriate patient population with …

Survival following implementation of next-generation sequencing in routine diagnostics of advanced lung cancer: Results of the German Network Genomic Medicine.

A Kostenko, SYF Michels, J Fassunke, M Scheffler… - 2016 - ascopubs.org
9085 Background: The Network Genomic Medicine (NGM) Lung Cancer is a health care
provider network offering comprehensive next generation sequencing (NGS)-based …

Benefits of NGS in Advanced Lung Adenocarcinoma Vary by Populations and Timing of Examination

PH Lee, WF Ou, YH Huang, KH Hsu, JS Tseng… - International Journal of …, 2024 - mdpi.com
Despite the widespread application of next-generation sequencing (NGS) in advanced lung
adenocarcinoma, its impact on survival and the optimal timing for the examination remain …

Next-generation sequencing for lung cancer

K Wu, RS Huang, L House, WC Cho - Future Oncology, 2013 - Taylor & Francis
Lung cancer is biologically aggressive and is the leading cause of cancer-related deaths.
The development of lung cancer is unique in each patient according to clinical …

[HTML][HTML] Clinical impact of hybrid capture–based next-generation sequencing on changes in treatment decisions in lung cancer

AB Rozenblum, M Ilouze, E Dudnik, A Dvir… - Journal of Thoracic …, 2017 - Elsevier
Introduction Targeted therapy significantly prolongs survival in lung adenocarcinoma.
Current diagnostic guidelines include only EGFR and anaplastic lymphoma receptor …